MAK068
MPO Colorimetric Activity Assay Kit
sufficient for 100 colorimetric tests
Sign Into View Organizational & Contract Pricing
All Photos(3)
Synonym(s):
Myeloperoxidase Colorimetric Activity Assay Kit
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer; cardiovascular diseases; hematological disorder
storage temp.
−20°C
Gene Information
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
Related Categories
General description
Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.
Application
MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.
Features and Benefits
Compatible with high-throughput handling systems.
Suitability
Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells
Principle
In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
188.6 °F
Flash Point(C)
87 °C
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Yannan Liu et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(5), G550-G563 (2014-07-19)
Understanding the regulation of death pathways, necrosis and apoptosis, in pancreatitis is important for developing therapies directed to the molecular pathogenesis of the disease. Protein kinase Cε (PKCε) has been previously shown to regulate inflammatory responses and zymogen activation in
Plasma nitration of high-density and low-density lipoproteins in chronic kidney disease patients receiving kidney transplants.
Bakillah A, et al.
Mediators of Inflammation, 2015 (2015)
Ruisong Pei et al.
Molecular nutrition & food research, 63(5), e1800985-e1800985 (2018-12-07)
Increased fruit consumption is associated with reduced risk of colitis. It has been investigated whether the anti-colitic effects of the polyphenol-rich aronia berry (Aronia mitschurinii 'Viking') are mediated through Th17 and Treg. Colitis is induced in recombinase activating gene-1 deficient
Esmat Rousta et al.
Nutrients, 13(10) (2021-10-24)
Commonly used synthetic dietary emulsifiers, including carboxymethylcellulose (CMC) and polysorbate-80 (P80), promote intestinal inflammation. We compared abilities of CMC vs. P80 to potentiate colitis and impact human microbiota in an inflammatory environment using a novel colitis model of ex-germ-free (GF)
Hammad A Ganatra et al.
Innate immunity, 23(1), 67-76 (2016-11-09)
Children with severe sepsis are known to have altered zinc homeostasis and decreased circulating zinc levels, suggesting a role for zinc supplementation to improve outcomes. We tested the hypothesis that zinc supplementation would improve survival in a juvenile model of
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service