Skip to Content
Merck
CN
All Photos(3)

Documents

Safety Information

MAK049

Sigma-Aldrich

Phosphatidylcholine Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Sign Into View Organizational & Contract Pricing

Synonym(s):
Phosphatidylcholine Test Kit
UNSPSC Code:
12161503
NACRES:
NA.84

usage

sufficient for 100 colorimetric or fluorometric tests

detection method

colorimetric
fluorometric

relevant disease(s)

neurological disorders; gastrointestinal diseases; cancer

storage temp.

−20°C

General description

Phosphatidylcholine (PC) accounts for more than 50% of the phospholipids composing mammalian plasma membranes and is particularly enriched in the extracellular leaflet. PC is synthesized in the liver and is required for lipoprotein assembly and secretion. PC is cleaved by phospholipase D, which hydrolyses the choline head, producing the signaling intermediate phosphatidic acid.

Application

Phosphatidylcholine Assay Kit has been used to determine the concentration of phosphatidylcholine in samples.

Suitability

Suitable for the measurement of phosphatidylcholine in a variety of biological samples

Principle

In this assay, PC concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the PC present.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Copper-64 labeled liposomes for imaging bone marrow.
Sang-gyu L, et al.
Nuclear Medicine and Biology, 43(12), 781-787 (2016)
Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats
Alena P, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(12), 1469-1480 (2017)
Michelle S Prew et al.
Nature communications, 13(1), 3669-3669 (2022-06-28)
Very long-chain acyl-CoA dehydrogenase (VLCAD) is an inner mitochondrial membrane enzyme that catalyzes the first and rate-limiting step of long-chain fatty acid oxidation. Point mutations in human VLCAD can produce an inborn error of metabolism called VLCAD deficiency that can
Amanda L Brown et al.
The Journal of nutrition, 150(4), 775-783 (2019-12-19)
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death in the world. Choline deficiency has been well studied in the context of liver disease; however, less is known about the effects of choline supplementation in HCC. The
Sang-Gyu Lee et al.
Nuclear medicine and biology, 43(12), 781-787 (2016-10-04)
Bone marrow is the soft tissue compartment inside the bones made up of hematopoietic cells, adipocytes, stromal cells, phagocytic cells, stem cells, and sinusoids. While [18F]-FLT has been utilized to image proliferative marrow, to date, there are no reports of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service