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MAK031

Sigma-Aldrich

Phosphate Fluorometric Kit

sufficient for 100 fluorometric tests

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.84

usage

sufficient for 100 fluorometric tests

detection method

fluorometric

storage temp.

−20°C

General description

Phosphate is an essential component in living organisms and contributes to a variety of biological functions, including structural roles within nucleic acids, cellular membranes and bone. Phosphate is also important in the transport of cellular energy, nucleic acid metabolism and signal transduction. Hyperphosphatemia, a condition of excess phosphate levels in the blood, can lead to calcification of organs and interference with usage of other inorganic ions, such as iron, calcium, magnesium and zinc.

Suitability

Suitable for the detection of inorganic phosphate (Pi) produced through reactions involving ATPases, GTPases, 5′-nucleotidase, protein phosphatases, acidand alkaline phosphatases, phosphorylase, etc. from a variety of samples

Principle

The Phosphate Fluorometric Assay Kit provides a simple and direct procedure for measuring phosphate in a variety of samples. Phosphate reacts with maltose to produce glucose in the presence of an enzyme. The glucose is subsequently oxidized and reacts with a probe, resulting in a fluorometric (λex = 535/λem = 587 nm) product proportional to the amount of phosphate present. This kit has a linear range of detection between 50-250 pmoles.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

Storage Class Code

10 - Combustible liquids

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup


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Advanced Biology for you. (2000)
Biochemical, Physiological, and Molecular Aspects of Human Nutrition-E-Book (2013)
Sara D Siegel et al.
mBio, 10(1) (2019-02-21)
The widely conserved LytR-CpsA-Psr (LCP) family of enzymes in Gram-positive bacteria is known to attach glycopolymers, including wall teichoic acid, to the cell envelope. However, it is undetermined if these enzymes are capable of catalyzing glycan attachment to surface proteins.
Fluid, Electrolyte and Acid-Base Disorders (2014)
Serum phosphate levels and mortality risk among people with chronic kidney disease.
Kestenbaum B, et al.
Journal of the American Society of Nephrology, 16(2), 520-528 (2005)

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