Skip to Content
Merck
CN

MAK014

Glucose-6-Phosphate Assay Kit

sufficient for 100 colorimetric tests

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

usage

sufficient for 100 colorimetric tests

detection method

colorimetric

relevant disease(s)

hematological disorder

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

General description

Glucose 6-phosphate (G6P) is a key metabolic intermediate that enters either metabolic pathways or storage. G6P is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

Application

Glucose-6-phosphate assay kit has been used in:

  • glucose 6-phosphate (G6P) assay
  • quantification of glucose-6-phosphate (G6P) and fructose-6-phosphate (F6P)
  • metabolite analysis
Suitable for quantifying Glucose-6-Phosphate in a variety of samples.

Biochem/physiol Actions

G6P is utilized by Glucose-6-phosphate dehydrogenase to generate reducing equivalents in the form of NADPH. This is particularly important in red blood cells where a G6PDH deficiency leads to hemolytic anemia. G6P is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional to the G6P present. Typical sensitivities of detection are between 1-30 nmoles.

pictograms

Health hazardCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

常规特殊物品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Guillermo Martín-Gutiérrez et al.
Antibiotics (Basel, Switzerland), 9(11) (2020-11-18)
Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in Escherichia coli are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulations by the selection
Quantification of organic P and low-molecular-weight organic acids in ferralsol soil extracts by ion chromatography
Kittima W, et al.
Geoderma, 257-258, 94-101 (2015)
Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.
Virtu C N, et al.
The Journal of Biological Chemistry, 290, 15581-15594 (2015)
Over expression of hyaluronan promotes progression of HCC via CD44-mediated pyruvate kinase M2 nuclear translocation
Li J H, et al.
American Journal of Cancer Research, 6(2), 509-521 (2016)
MiR-182 promotes glucose metabolism by upregulating hypoxia-inducible factor 1a in NSCLC cells
Mingliang W, et al.
Biochemical and Biophysical Research Communications, 504(2), 400-405 (2018)

Articles

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

本页面介绍了一篇有关瓦博格效应的文章,以及其如何能够在正常氧气水平下,增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明,癌细胞显示出对糖酵解的依赖性增加,以满足他们的能量需求,无论是否有充足的氧气存在。

Related Content

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service