MAK004
Glutamate Assay Kit
sufficient for 100 colorimetric tests
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All Photos(2)
Synonym(s):
L-Glutamate Assay Kit
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
usage
sufficient for 100 colorimetric tests
application(s)
cosmetics
food and beverages
detection method
colorimetric
relevant disease(s)
neurological disorders; cancer
storage temp.
−20°C
Related Categories
General description
Glutamate, one of the two acidic proteinogenic amino acids, is also a key molecule in cellular metabolism. The synthesis of α-KG from glutamate by glutamate dehydrogenase is a key TCA cycle anaplerotic reaction. In humans, glutamate plays an important role both in amino acid degradation and disposal of excess or waste nitrogen. Within the mammalian nervous system, glutamate is the most abundant excitatory neurotransmitter. It is believed to be involved in learning and memory and may also be involved in diseases like amyotrophic lateral sclerosis, autism, some forms of mental retardation, and Alzheimer′s disease. Glutamate is present in a wide variety of foods, and has been used as a flavor enhancer in food industry.
Application
Glutamate Assay Kit has been used to determine the concentration of glutamate in cerebrospinal fluid in a rat subarachnoid hemorrhage model. It has also been used to determine cytosolic and secreted glutamate concentrations in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.
Suitability
Suitable to determine glutamate concentration in a variety of samples.
Principle
Glutamate concentration is determined by an enzymatic assay, which results in a colorimetric (450 nm) product, proportional to the glutamate present.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
WGK
WGK 3
Regulatory Information
动植物源性产品
Certificates of Analysis (COA)
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Developing medications targeting glutamatergic dysfunction in autism: progress to date.
Fung L K and Antonio Y H
CNS Drugs, 29(6), 453-463 (2015)
Glutamate, at the interface between amino acid and carbohydrate metabolism.
Brosnan J T.
The Journal of Nutrition, 130(4), 988S-990S (2000)
Glutamate as a neurotransmitter in the healthy brain.
Zhou Y and Danbolt N C
Journal of Neural Transmission. General Section, 121(8), 799-817 (2014)
J Jašprová et al.
Scientific reports, 8(1), 7444-7444 (2018-05-12)
Phototherapy was introduced in the early 1950's, and is the primary treatment of severe neonatal jaundice or Crigler-Najjar syndrome. Nevertheless, the potential biological effects of the products generated from the photodegradation of bilirubin during phototherapy remain unknown. This is very
The GluN1/GluN2B NMDA receptor and metabotropic glutamate receptor 1 negative allosteric modulator has enhanced neuroprotection in a rat subarachnoid hemorrhage model.
Zhang Z, et al.
Experimental Neurology, 301, 13-25 (2018)
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