Application
Mimetic columns are used in affinity chromatography and protein chromatography. Mimetic columns have been used in studies to develop anti-inflammatory therapeutics.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
WGK
WGK 1
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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K Clark et al.
FEBS letters, 471(2-3), 182-186 (2000-04-18)
Integrin alpha4beta1 is a major leukocyte adhesion receptor that is a key target for the development of anti-inflammatory therapeutics. With the dual long-term goals of developing a reagent for use in high-throughput inhibitor screening assays and for crystallisation trials and
Tsutomu Arakawa et al.
Protein expression and purification, 63(2), 158-163 (2008-10-14)
MEP HyperCel resin, one of the Protein-A mimetic columns, is designed to bind antibodies at physiological pH and elutes the bound antibodies at mildly acidic pH. We have tested aqueous arginine solution for washing and elution of the resin. To
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