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Merck
CN

M7771

N-Methoxysuccinyl-Ala-Ala-Pro-Met p-nitroanilide

>95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C27H38N6O9S
CAS Number:
70967-91-8
Molecular Weight:
622.69
UNSPSC Code:
12352202
PubChem Substance ID:
24897180
MDL number:
MFCD00077134

Key Documents

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InChI

1S/C27H38N6O9S/c1-16(28-22(34)11-12-23(35)42-3)24(36)29-17(2)27(39)32-14-5-6-21(32)26(38)31-20(13-15-43-4)25(37)30-18-7-9-19(10-8-18)33(40)41/h7-10,16-17,20-21H,5-6,11-15H2,1-4H3,(H,28,34)(H,29,36)(H,30,37)(H,31,38)

SMILES string

COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCSC)C(=O)Nc2ccc(cc2)N(=O)=O

InChI key

LUUQUDLEABXXQL-UHFFFAOYSA-N

assay

>95% (HPLC)

form

solid

storage temp.

−20°C

Gene Information

human ... CTSG(1511)
mouse ... CTSG(13035)
rat ... CTSG(290257)

General description

Colorimetic substrate for cathepsin G.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
117H0311
096H0338
028H0781
108H1198
066H0031

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Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.
K Nakajima et al.
The Journal of biological chemistry, 254(10), 4027-4032 (1979-05-25)
Jorge Frias et al.
Journal of microbiology and biotechnology, 31(2), 327-337 (2020-11-06)
Fibrinolytic enzymes with a direct mechanism of action and safer properties are currently requested for thrombolytic therapy. This paper reports on a new enzyme capable of degrading blood clots directly without impairing blood coagulation. This enzyme is also non-cytotoxic and

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