M7765
1-Oleoyl-rac-glycerol
≥99%
Synonym(s):
MG(18:1(9Z)/0:0/0:0)[rac], 1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate, DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein
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About This Item
Linear Formula:
CH3(CH2)7CH=CH(CH2)7COOCH2CHOHCH2OH
CAS Number:
Molecular Weight:
356.54
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-827-7
Beilstein/REAXYS Number:
1728976
MDL number:
biological source
synthetic (organic)
Quality Level
description
non-ionic
assay
≥99%
form
powder
mp
35 °C
functional group
ester
lipid type
neutral glycerides
shipped in
wet ice
storage temp.
−20°C
SMILES string
O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key
RZRNAYUHWVFMIP-KTKRTIGZSA-N
General description
1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.
Application
1-Oleoyl-rac-glycerol has been used:
- to mix with the sample by two-syringe method, to achieve lipidic cubic phase in crystallization technique
- as a substrate for monoglyceride (MG) lipase assay
- in the preparation of MG solution for the measurement of in vitro MG hydrolase activity
Biochem/physiol Actions
1-Oleoyl-rac-glycerol shows both inhibition and anti-inhibition action on the lipoprotein lipase mediated triglyceride hydrolysis.
Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
309.2 °F - closed cup
flash_point_c
154.0 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Product Information Sheet
Assays of lipolytic enzymes
Adipose Tissue Protocols, 97-119 (2001)
Measurement of lipolysis
Methods in Enzymology, 538, 171-193 (2014)
Thomas G Meikle et al.
Journal of colloid and interface science, 587, 90-100 (2020-12-29)
The growing global threat of antimicrobial resistance, combined with the slowed development of novel antibiotics, has resulted in a critical need for new antimicrobial therapies. Naturally occurring antimicrobial peptides (AMPs) can act as highly potent, broad-spectrum antibiotics which may be
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M7765-100MG | 04061834062370 |
| M7765-1G | 04061834062387 |
| M7765-25MG | 04061834062394 |
| M7765-50MG | 04061834062400 |