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Merck
CN

M7008

4-Methylumbelliferyl-β-D-xylopyranoside

β-xylosidase substrate, fluorogenic, ≥98% (HPLC), powder

Synonym(s):

4-Methylumbelliferyl β-D-xyloside

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About This Item

Empirical Formula (Hill Notation):
C15H16O7
CAS Number:
6734-33-4
Molecular Weight:
308.28
NACRES:
NA.32
PubChem Substance ID:
24897133
UNSPSC Code:
12352204
EC Number:
229-784-4
MDL number:
MFCD00037607
Beilstein/REAXYS Number:
39934

Key Documents

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Product Name

4-Methylumbelliferyl-β-D-xylopyranoside, β-xylosidase substrate

InChI key

JWIYLOHVJDJZOQ-KAOXEZKKSA-N

InChI

1S/C15H16O7/c1-7-4-12(17)22-11-5-8(2-3-9(7)11)21-15-14(19)13(18)10(16)6-20-15/h2-5,10,13-16,18-19H,6H2,1H3/t10-,13+,14-,15+/m1/s1

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)ccc12

assay

≥98% (HPLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

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General description

A substrate for β-xylosidase

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000518141
0000518140
0000518140
0000518141
0000508545

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K Takagaki et al.
Journal of biochemistry, 119(4), 697-702 (1996-04-01)
Human skin fibroblasts were incubated in the presence of a fluorogenic xyloside, 4-methyl-umbelliferyl-beta-D-xyloside (Xyl-MU), then the cultured medium was recovered, concentrated with a lyophilizer, and dialyzed against distilled water. The structures of the Xyl-MU derivatives purified from the dialyzable fraction
Loontiens, F.G. and DeBruyne, C.K.
Naturwissenschaften, 52, 661-661 (1965)
H H Freeze et al.
The Journal of biological chemistry, 268(3), 1618-1627 (1993-01-25)
beta-D-Xylosides are often used to competitively inhibit proteoglycan synthesis by serving as primers for free glycosaminoglycan (GAG) chain assembly. Quite unexpectedly, we found that when human melanoma cells and Chinese hamster ovary cells are labeled with [3H] galactose in the
S Shibata et al.
The Journal of biological chemistry, 270(23), 13794-13798 (1995-06-09)
4-Methylumbelliferyl-beta-D-xyloside (Xyl-MU) was added to the medium of cultured human skin fibroblasts. After incubation, the culture medium was pooled, and the Xyl-MU-induced oligosaccharides in the medium were purified by gel filtration chromatography. A novel Xyl-MU derivative was obtained, in addition
W G Hill et al.
Biochimica et biophysica acta, 1454(2), 174-182 (1999-06-25)
The ability of cells to decorate glycosaminoglycans (GAGs) with sulphate in highly specific patterns is important to extracellular matrix biogenesis and placing appropriate glycosulphated ligands on the cell surface. We have examined sulphate metabolism in two pancreatic duct epithelial cell
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Product Information Sheet - M7008

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