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M6385

Sigma-Aldrich

Methyl cellulose

viscosity: 25 cP

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CAS Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

form

powder

color

white to off-white

viscosity

20-30 cP, 2 % in water(20 °C)

SMILES string

[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]

InChI key

YLGXILFCIXHCMC-JHGZEJCSSA-N

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General description

Methyl cellulose (MC) is a simple derivative of cellulose.

Application

Methyl cellulose has been used:
  • as a supplement for culturing multicellular spheroids of SH-SY5Y cells
  • as a supplement for culturing tumor cell spheroids
  • to generate and study the rheological behavior of aqueous mullite-albumin-methylcellulose systems

Biochem/physiol Actions

Methyl cellulose (MC) acts as a laxative and is hydrophilic. It has therapeutic effects against constipation, irritable bowel syndrome, and diverticulosis due to its bulk-forming and stool softening properties. MC has the potential to treat patients with ileostomies and colostomies. It may also be used as a stabilizer and emulsifier. MC is a component of eye drops and contact lens solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rheological behavior of aqueous mullite-albumin-methylcellulose systems
Sandoval M, et al.
Ceramics International, 43(9) (2017)
Jesse E Hanson et al.
Cell reports, 30(2), 381-396 (2020-01-16)
NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR function via allosteric modulation are largely unknown. We examine the in vivo effects
Methylcellulose
Kieth H.
xPharm: The Comprehensive Pharmacology Reference, 1-3 (2007)
Methylcellulose, a cellulose derivative with original physical properties and extended applications
Nasatto P L, et al.
Polymers, 7(5), 777-803 (2015)
Eyedrops and ointments
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 220-221 (2016)

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