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M6020

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

Synonym(s):

D-Mannopyranose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
3458-28-4
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
24897068
EC Number:
222-392-4
Beilstein/REAXYS Number:
1564373
MDL number:
MFCD00064122
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biological source

plant (Spruce, Birch or Beech Wood, Glucose)

Quality Level

300

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

133-140 °C (lit.)

solubility

H2O: 50 mg/mL

application(s)

advanced drug delivery
agriculture

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Application

D-(+)-Mannose has been used:
  • as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
  • as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
  • in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

Biochem/physiol Actions

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP2337
BCCP1847
BCCP5607
BCCP1297
BCCN8822

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Articles

Pharmaceutical Research Applications of Carbohydrates and Polysaccharides

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Carbohydrates as Versatile Enablers of Advanced Drug Delivery Systems

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.

Metabolic manipulation of glycosylation disorders in humans and animal models
Freeze HH and Sharma V
Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)
M J Carlino et al.
Gut microbes, 12(1), 1-21 (2020-11-03)
Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study
Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos
Transgenic Plants, 109-122 (2012)
View All Related Papers

Global Trade Item Number

SKUGTIN
M6020-100G04061834518518
M6020-500G04061835568925
M6020-25G04061835568918