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Merck
CN

M5760

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

>97.5% purity (HPLC), powder

Synonym(s):

4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole, MBD

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About This Item

Empirical Formula (Hill Notation):
C14H12N4O4
CAS Number:
33984-50-8
Molecular Weight:
300.27
NACRES:
NA.47
PubChem Substance ID:
24897041
UNSPSC Code:
12171500
EC Number:
251-775-9
MDL number:
MFCD00042778
Beilstein/REAXYS Number:
1151390

Key Documents

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Product Name

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan,

InChI key

IENONFJSMWUIQQ-UHFFFAOYSA-N

InChI

1S/C14H12N4O4/c1-21-10-4-2-9(3-5-10)8-15-11-6-7-12(18(19)20)14-13(11)16-22-17-14/h2-7,15H,8H2,1H3

SMILES string

COc1ccc(CNc2ccc([N+]([O-])=O)c3nonc23)cc1

assay

>97.5% (HPLC)

form

powder

color

orange to red

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

Quality Level

100

Related Categories

Application

Fluorescent probe for hydrophobic (non-polar) regions in proteins and nucleoproteins.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKBR6862V
MKBR8092V
051M1274V
051M1273V
SLBG6369V

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Benjamin C Buchmuller et al.
Scientific reports, 10(1), 4053-4053 (2020-03-07)
5-Methylcytosine (mC) exists in CpG dinucleotides of mammalian DNA and plays key roles in chromatin regulation during development and disease. As a main regulatory pathway, fully methylated CpG are recognized by methyl-CpG-binding domain (MBD) proteins that act in concert with
Yu Nakamichi et al.
Scientific reports, 9(1), 6466-6466 (2019-04-25)
Despite extensive research on primate cognitive function, understanding how anatomical connectivity at a neural circuit level relates to information transformation across different cortical areas remains primitive. New technology is needed to visualize inter-areal anatomical connectivity in living monkeys and to
Sevda Tanrıkulu-Küçük et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 44(7), 774-782 (2019-01-04)
This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). The control group was fed a
Angharad R Morgan et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 15(6), 776-787 (2019-05-03)
Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. A hypothesis-led plasma biomarker search was conducted in the context of international multicenter studies. The discovery
Andaine Seguin-Orlando et al.
Scientific reports, 5, 11826-11826 (2015-07-03)
The recent discovery that DNA methylation survives in fossil material provides an opportunity for novel molecular approaches in palaeogenomics. Here, we apply to ancient DNA extracts the probe-independent Methylated Binding Domains (MBD)-based enrichment method, which targets DNA molecules containing methylated
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