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Safety Information

M5685

Sigma-Aldrich

Metrazoline

solid

Synonym(s):

4,5-Dihydro-2-[(1E)-2-(2-methylphenyl)ethenyl-1H-imidazole oxalate salt

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About This Item

Linear Formula:
C12H14N2·C2H2O4
CAS Number:
221225-04-3
Molecular Weight:
276.29
MDL number:
MFCD03787984
UNSPSC Code:
12352202
PubChem Substance ID:
24278559
NACRES:
NA.77

form

solid

solubility

H2O: 16 mg/mL

SMILES string

CC1=CC=CC=C1/C=C/C2=NCCN2.OC(C(O)=O)=O

InChI

1S/C12H14N2.C2H2O4/c1-10-4-2-3-5-11(10)6-7-12-13-8-9-14-12;3-1(4)2(5)6/h2-7H,8-9H2,1H3,(H,13,14);(H,3,4)(H,5,6)/b7-6+;

InChI key

QDUUQIGHAAEJDO-UHDJGPCESA-N

Biochem/physiol Actions

Potent and selective imidazoline binding site ligand

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
090K4702

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C Polidori et al.
European journal of pharmacology, 392(1-2), 41-49 (2000-04-05)
Previous studies have suggested that imidazoline I(2) receptors play a role in feeding control in rats. The effect of subcutaneous (s.c.) injections of four novel imidazoline I(2) ligands, 2-naphthalen-2yl-4,5-dihydro-1H-imidazole hydrochloride (benazoline), 2-styryl-4,5-dihydro-1H-imidazole oxalate (tracizoline), o-nitro-tracizoline and o-methyl-tracizoline (metrazoline) on food

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