M5001
1-Methyladenosine
Synonym(s):
N1-Methyladenosine
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About This Item
Empirical Formula (Hill Notation):
C11H15N5O4
CAS Number:
Molecular Weight:
281.27
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
InChI
1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1
SMILES string
CN1C=Nc2c(ncn2[C@@H]3O[C@@H](CO)[C@H](O)[C@@H]3O)C1=N
InChI key
GFYLSDSUCHVORB-IOSLPCCCSA-N
storage temp.
−20°C
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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H Grosjean et al.
Nucleic acids research, 23(21), 4312-4319 (1995-11-11)
Transfer RNAs of the extreme halophile Haloferax volcanii contain several modified nucleosides, among them 1-methylpseudouridine (m1 psi), pseudouridine (psi), 2'-0-methylcytosine (Cm) and 1-methylinosine (m1l), present in positions 54, 55, 56 and 57 of the psi-loop, respectively. At the same positions
I Honda et al.
The Tohoku journal of experimental medicine, 188(2), 133-138 (1999-10-20)
The elevation of urinary modified nucleosides levels in urine is found in patients with cancers. In the present study, we have tested 616 urine samples randomly collected from non-malignant cases. Thirty-two percent (194/616) and 11% (68/616) had elevated levels of
Sonia Scorrano et al.
Analytica chimica acta, 659(1-2), 167-171 (2010-01-28)
A highly selective molecularly imprinted polymer (MIP) for 1-methyladenosine (1-MA), an urinary modified nucleoside used as cancer marker, was prepared and its use as solid-phase extraction (SPE) sorbent material was demonstrated. The MIP was prepared by a very simple procedure
Feng Chen et al.
Analytical and bioanalytical chemistry, 401(6), 1899-1904 (2011-08-13)
Late diagnosis of hepatocarcinoma (HCC) is one of the most primary factors for the poor survival of patients. Thereby, identification of sensitive and specific biomarkers for HCC early diagnosis is of great importance in biological medicine to date. In the
A Gobbetti et al.
The Journal of endocrinology, 152(1), 141-146 (1997-01-01)
The presence of pituitary adenylate cyclase-activating peptide (PACAP) 38-immuno-like material (PACAP 38-IL) in the brain and ovary of the crested newt, Triturus carnifex, and its action on ovarian steroidogenesis and prostaglandin synthesis were evaluated. The HPLC, brain and ovary extract
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