M4939
Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 Rat, Mouse
≥97% (HPLC)
Recommended Products
Quality Level
Assay
≥97% (HPLC)
form
powder
color
white
application(s)
cell analysis
storage temp.
−20°C
Gene Information
mouse ... Mog(17441)
rat ... Mog(24558)
Related Categories
Amino Acid Sequence
General description
Application
- Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis.: This paper investigates the delayed therapeutic administration of erythropoietin and its derivatives in the treatment of autoimmune encephalomyelitis, using Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 to induce the disease model in mice (Savino et al., 2006).
- Absence of reuptake of serotonin influences susceptibility to clinical autoimmune disease and neuroantigen-specific interferon-gamma production in mouse EAE.: This research explores the role of serotonin reuptake in modulating immune responses and susceptibility to autoimmune diseases, using Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 to induce experimental autoimmune encephalomyelitis in mice (Hofstetter et al., 2005).
- Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.: The study demonstrates the effectiveness of trichostatin A, a histone deacetylase inhibitor, in treating experimental autoimmune encephalomyelitis. Myelin Oligodendrocyte Glycoprotein Peptide Fragment 35-55 was used to induce the disease model in rats and mice, providing insights into potential epigenetic therapies (Camelo et al., 2005).
Biochem/physiol Actions
Other Notes
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the difference between peptide content and purity of Product No. M4939?
If a given lot of Product No. M4939 has, say, a peptide content of 85% and purity of 99%, this means that 85% of the vial content is the peptide, the remaining being water and trifluoroacetate salts. Of the 85% that is the peptide, 99% is Myelin oligodendroctye glycoprotein peptide fragment (35-55).
For how long is a solution of this peptide (Product No. M4939) stable?
Sigma-Aldrich has not performed any solution stability studies on M4939, so we do not have information as to whether solutions are stable refrigerated or frozen.
What can I use to dissolve this peptide (Product No. M4939)?
Every lot is tested for solubility at a concentration of 1 mg/mL, using either 1% acetic acid or water, resulting in a clear, colorless solution. The peptide is also soluble in an aqueous buffer such as 0.01 M PBS, pH 7.4, but we do not know whether it is equally as soluble in these buffers as it is in dilute acetic acid or water.
Can I combine this peptide (Product No. M4939) with an adjuvant to prepare an immunizing emulsion?
Unfortunately, we have no data based on our own studies or on literature references on Product No. M4939 to answer this question.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service