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Safety Information

M4542

Sigma-Aldrich

Melanin Concentrating Hormone rat

≥90% (HPLC)

Synonym(s):

MCH

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About This Item

Empirical Formula (Hill Notation):
C105H160N30O26S4
CAS Number:
128315-56-0
Molecular Weight:
2386.84
MDL number:
MFCD00080193
UNSPSC Code:
51111800
PubChem Substance ID:
329817901
NACRES:
NA.32

biological source

synthetic (organic)

Assay

≥90% (HPLC)

form

powder

composition

Peptide content, ≥70%

solubility

water: 1 mg/mL, clear, colorless

UniProt accession no.

P14200

shipped in

ambient

storage temp.

−20°C

SMILES string

CSCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(C)C)NC1=O)C(C)C)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc6ccccc6)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C105H160N30O26S4/c1-53(2)42-70-86(144)118-50-80(138)119-64(24-16-36-114-103(108)109)90(148)133-83(55(5)6)100(158)130-73(45-58-28-30-60(136)31-29-58)93(151)124-69(26-18-38-116-105(112)113)101(159)135-39-19-27-78(135)99(157)132-77(98(156)128-74(46-59-49-117-63-23-15-14-22-61(59)63)95(153)121-66(32-33-79(107)137)91(149)134-84(56(7)8)102(160)161)52-165-164-51-76(97(155)123-68(35-41-163-10)88(146)126-70)131-87(145)65(25-17-37-115-104(110)111)120-92(150)71(43-54(3)4)127-89(147)67(34-40-162-9)122-96(154)75(48-82(141)142)129-94(152)72(44-57-20-12-11-13-21-57)125-85(143)62(106)47-81(139)140/h11-15,20-23,28-31,49,53-56,62,64-78,83-84,117,136H,16-19,24-27,32-48,50-52,106H2,1-10H3,(H2,107,137)(H,118,144)(H,119,138)(H,120,150)(H,121,153)(H,122,154)(H,123,155)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,156)(H,129,152)(H,130,158)(H,131,145)(H,132,157)(H,133,148)(H,134,149)(H,139,140)(H,141,142)(H,160,161)(H4,108,109,114)(H4,110,111,115)(H4,112,113,116)/t62-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-/m0/s1

InChI key

MWLPXSMFEPHETN-QRXCLJFASA-N

Gene Information

rat ... Pmch(24659)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLBS8970
SLBM8504V
SLBM2274V
SLBL9018V
SLBB5987V

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Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
Dietmar Bachner
Febs Letters (1999)
Melanin-concentrating hormone functions in the nervous system: food intake and stress.
Hervieu G
Expert Opinion on Therapeutic Targets (2003)
Wenting Cheng et al.
Talanta, 219, 121242-121242 (2020-09-06)
Growing evidence suggests that exosomes-encapsulated miRNAs detection is of paramount significance in early diagnostics of cancer due to protection from degradation by ribonuclease. However, exosomal microRNAs with low abundance and subtle variation have restricted their clinical application. Herein, an electrochemical
Melanin-concentrating hormone induces insulin resistance through a mechanism independent of body weight gain
Marcio P
The Journal of Endocrinology (2005)
Melanin concentrating hormone induces hippocampal acetylcholine release via the medial septum in rats.
Peptides (2013)
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