M4446
Metanil yellow solution
0.25%
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About This Item
Empirical Formula (Hill Notation):
C18H14N3NaO3S
CAS Number:
Molecular Weight:
375.38
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Colour Index Number:
13065
InChI
1S/C18H15N3O3S.Na/c22-25(23,24)18-8-4-7-17(13-18)21-20-16-11-9-15(10-12-16)19-14-5-2-1-3-6-14;/h1-13,19H,(H,22,23,24);/q;+1/p-1/b21-20+;
InChI key
NYGZLYXAPMMJTE-ANVLNOONSA-M
concentration
0.25%
General description
Metanil yellow is an azo dye, which is used as a counterstain in PAS (periodic acid-Schiff) or iron-hematoxylin stained sections to increase contrast. At pH 1.2, metanil yellow is red in color, whereas in pH 2.3, it is yellow in color.
Application
Cytoplasmic stain. Counterstain for mucicarmine stains.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Enhancement of histological detail using metanil yellow as counterstain in periodic acid Schiff's hematoxylin staining of glycol methacrylate tissue sections.
Quintero-Hunter I, et al.
Biotechnic & Histochemistry, 66(4), 169-172 (1991)
Photocatalytic degradation of azo dye Metanil Yellow: Optimization and kinetic modeling using a chemometric approach.
Sleiman M, et al.
Applied Catalysis. B, Environmental, 77(1-2), 1-11 (2007)
R W Sabnis.
Handbook of Acid-Base Indicators, 416-416 (2007)
M Das et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 35(8), 835-838 (1997-08-01)
Metanil yellow, a non-permitted food colour, has been found in various foodstuffs. The induction potential of metanil yellow on hepatic microsomal cytochrome P-450 (P-450)-dependent monooxygenases and cytosolic detoxification enzymes, namely, glutathione S-transferase (GST) and quinone reductase (QR), was investigated. Oral
M Sundarrajan et al.
Toxicology letters, 116(1-2), 119-130 (2000-07-25)
Metanil yellow (MY) and Malachite green (MG) are textile dyes, which, despite the ban, occur unscrupulously as food colouring agents. Accordingly they constitute a serious public health hazard and are of sufficient environmental concern. We have earlier reported that both
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