M4154
β-N-Methylamino-L-alanine hydrochloride
Synonym(s):
L-BMAA
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About This Item
Empirical Formula (Hill Notation):
C4H10N2O2 · HCl
CAS Number:
Molecular Weight:
154.60
MDL number:
UNSPSC Code:
12352200
Recommended Products
storage temp.
2-8°C
SMILES string
CNCC(N)C(O)=O
Biochem/physiol Actions
Neuroexcitotoxic amino acid; may be involved in Guam amyotrophic lateral sclerosis
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Shark fin consumption may expose people to neurotoxic BMAA.
Wendee Holtcamp
Environmental health perspectives, 120(5), A191-A191 (2012-05-03)
W Broc Glover et al.
Analytical chemistry, 84(18), 7946-7953 (2012-08-22)
β-methylamino-l-alanine (BMAA) is a naturally occurring nonprotein amino acid originally discovered in cycad seeds and traditional foods of the Chamorro people of Guam. Recent research has implicated BMAA as a potential factor in neurodegenerative disease and described the production of
Liying Jiang et al.
Analytical and bioanalytical chemistry, 405(4), 1283-1292 (2012-11-28)
The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) is an amino acid that is putatively associated with the pathology of amyotrophic lateral sclerosis/Parkinsonism-dementia complex (ALS-PDC) disease. It raises serious health risk concerns since cyanobacteria are ubiquitous thus making human exposure almost inevitable. The
Blue-green algae or cyanobacteria in the intestinal micro-flora may produce neurotoxins such as Beta-N-Methylamino-L-Alanine (BMAA) which may be related to development of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinson-Dementia-Complex in humans and Equine Motor Neuron Disease in horses.
Steven R Brenner
Medical hypotheses, 80(1), 103-103 (2012-11-14)
The emerging science of BMAA: do cyanobacteria contribute to neurodegenerative disease?
Wendee Holtcamp
Environmental health perspectives, 120(3), A110-A116 (2012-03-03)
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