Skip to Content
Merck
CN

M4008

Morin hydrate

antioxidant, powder

Synonym(s):

2′,3,4′,5,7-Pentahydroxyflavone

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H10O7 · xH2O
CAS Number:
654055-01-3
Molecular Weight:
302.24 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
24278552
UNSPSC Code:
12171500
EC Number:
207-542-9
MDL number:
MFCD00217054

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Morin hydrate, powder

InChI key

MYUBTSPIIFYCIU-UHFFFAOYSA-N

InChI

1S/C15H10O7.H2O/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15;/h1-5,16-19,21H;1H2

SMILES string

O.Oc1ccc(c(O)c1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

form

powder

color

yellow

solubility

methanol: 50 mg/mL

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Morin hydrate has been used:
  • to investigate its antitumor functionality using cell viability and apoptosis assay in human cancer cell lines.
  • as a fluorescence stain to detect aluminum in motor neurons and lumbar cord.
  • to study its protective effect on neuronal hearing loss and on neural stem cells (NSCs) proliferation and differentiation

Biochem/physiol Actions

Morin hydrate is a flavonoid with antioxidant properties. It has been shown to protect cells against oxygen radical damage. Morin not only scavenges oxyradicals, but also moderately inhibits xanthine oxidase, a free-radical generating enzyme. At concentrations of 75-100 micromolar, morin inhibits oxidation of low density lipoprotein (LDL) by free radicals or Cu2+. Morin has been reported to inhibit rat brain phospha­tidyl­inositol­phos­phate kinase activity in vitro and in vivo.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ8848
MKCX2978
MKCW3839
MKCV7298
MKCW0670

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

T W Wu et al.
Life sciences, 58(2), PL 17-PL 22 (1996-01-01)
We demonstrated that the flavonoid morin hydrate at 75-100 microM protects against the oxidation of low density lipoprotein (LDL) by free radicals produced by 2,2'-azo-bis(2-amidinopropane) dihydrochloride. Morin hydrate reduces the relative electrophoretic mobility, malondialdehyde equivalents and lipid peroxide level of
Christopher A Shaw et al.
Journal of inorganic biochemistry, 103(11), 1555-1562 (2009-09-11)
Gulf War Syndrome is a multi-system disorder afflicting many veterans of Western armies in the 1990-1991 Gulf War. A number of those afflicted may show neurological deficits including various cognitive dysfunctions and motor neuron disease, the latter expression virtually indistinguishable
T W Wu et al.
Biochemical pharmacology, 49(4), 537-543 (1995-02-14)
Morin hydrate is a bioactive pigment found in yellow Brazil wood. Recently, we reported that morin hydrate prolongs the survival of three types of cells from the human circulatory system against oxyradicals generated in vitro. The protection excels that given
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
Shaw CA and Petrik MS
Journal of Inorganic Biochemistry, 103(11), 1555-1562 (2009)
Shan Yu et al.
Inflammation, 43(4), 1293-1303 (2020-03-07)
Mastitis is one of the most common diseases that both affects human and animals. Morin is derived from the member of Moraceae family, which has been used in the treatment of many inflammatory diseases. The purpose of this study was
View All Related Papers

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service