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Key Documents

Safety Information

M3441

Sigma-Aldrich

Midkine, human

≥90% (SDS-PAGE)

Synonym(s):

Heparin-binding growth/differentiation factor

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

biological source

synthetic

Quality Level

Assay

≥90% (SDS-PAGE)

packaging

pkg of 50 μg

color

white

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MDK(4192)

Biochem/physiol Actions

Midkine, a heparin-binding growth factor, contains 121 amino acid residues with 5 disulfide bonds. It promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. The C-terminal portion contains the heparin-binding domain and the antigenicity and neurite-promoting sequences. Both the C- and N-terminals are necessary for the molecule′s neurotrophic effects.
Promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. The C-terminal portion contains the heparin-binding domain and the antigenicity and neurite-promoting sequences. Both the C- and N-terminals are necessary for the molecule′s neurotrophic effects.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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