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M3409

Sigma-Aldrich

Magnesium sulfate solution

for molecular biology, 1.00 M±0.04 M

Synonym(s):

Magnesium Sulphate, Magnesium(II) sulfate, MgSO4

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About This Item

Empirical Formula (Hill Notation):
MgSO4
CAS Number:
7487-88-9
Molecular Weight:
120.37
MDL number:
MFCD00011110
UNSPSC Code:
12352302
PubChem Substance ID:
24896841
NACRES:
NA.31

grade

for molecular biology

Quality Level

200

sterility

0.2 μm filtered

form

liquid

concentration

1.00 M±0.04 M

cation traces

heavy metals (as Pb): ≤5 ppm

foreign activity

DNase, RNase, nickase and protease, none detected

SMILES string

[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChI key

CSNNHWWHGAXBCP-UHFFFAOYSA-L

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Application

Magnesium sulfate solution has been used:
  • as a component in super optimal broth with catabolite repression (SOC) medium for culturing Escherichia coli
  • as a component in transition media for culturing human umbilical vein endothelial cells (HUVEC)]
  • as a component in M9 buffer for worm fixation prior to nuclei extraction

Biochem/physiol Actions

Magnesium sulfate has anti-convulsant, anti-inflammatory and vasodilatory properties. Magnesium sulfate relaxes smooth muscles. In acute asthma patients, use both intravenous and nebulization of magnesium sulfate as additive treatment improves pulmonary function. Magnesium sulfate reduces preterm labor in high risk pregnant women.

Preparation Note

Prepared in 18 megohm water

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bio-protocol, 4(24), e1358-e1358 (2014)
Method for multiplexing CRISPR/Cas9 in Saccharomyces cerevisiae using artificial target DNA sequences
Giersch RM and Finnigan GC
Bio-protocol, 7(18), 321-330 (2017)
The value of magnesium sulfate nebulization in treatment of acute bronchial asthma during pregnancy
Badawy MSH and Hassanin IMA
The Egyptian journal of chest diseases and tuberculosis, 63(2), 285-289 (2014)
Estrogen decreases TNF-alpha and oxidized LDL induced apoptosis in endothelial cells
Florian M and Magder S
Steroids, 73(1), 47-58 (2008)
Lex W Doyle
Current opinion in pediatrics, 24(2), 154-159 (2012-01-10)
Antenatal magnesium sulfate may reduce the excessive rates of cerebral palsy in survivors of very preterm birth. There are five randomized controlled trials of magnesium sulfate therapy given to the mother prior to very preterm birth which have reported neurological
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