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Merck
CN

M2015

1-Stearoyl-rac-glycerol

≥99%

Synonym(s):

MG(18:0/0:0/0:0)[rac], 1-Monooctadecanoyl-rac-glycerol, rac-Glycerol 1-stearate, DL-α-Stearin, Monostearin

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About This Item

Linear Formula:
CH3(CH2)16COOCH2CH(OH)CH2OH
CAS Number:
123-94-4
Molecular Weight:
358.56
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
24896595
EC Number:
204-664-4
Beilstein/REAXYS Number:
1728685
MDL number:
MFCD00036186

Key Documents

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Product Name

1-Stearoyl-rac-glycerol, ≥99%

form

powder

InChI key

VBICKXHEKHSIBG-UHFFFAOYSA-N

InChI

1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

biological source

synthetic (organic)

assay

≥99%

functional group

phospholipid

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

Quality Level

200

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Application

Monostearin (1-Stearoyl-rac-glycerol) is used in the development of drug delivery vehicles such as nanoparticles and microemulsions.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000510050
0000510050
0000481770
0000481770
0000484484

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Sheng Tan et al.
Drug design, development and therapy, 11, 3519-3529 (2017-12-22)
Erlotinib (ETB) is a well-established therapeutic for non-small-cell lung cancer (NSCLC). To overcome drug resistance and severe toxicities in the clinical application, redox-responsive and pH-sensitive nanoparticle drug delivery systems were designed for the encapsulation of ETB. Poly(acrylic acid)-cystamine-oleic acid (PAA-ss-OA)
Maria Christina Camasmie Peters et al.
Journal of drug targeting, 28(3), 259-270 (2019-09-07)
Nanocrystals and lipid-based nanosystems have the potential to play a crucial role in a significant shift in the treatment of ophthalmic diseases. These drug delivery systems allow overcoming the barriers imposed by anatomy and physiology of the organ of vision.
Howida Kamal Ibrahim et al.
Drug delivery, 23(9), 3181-3192 (2016-03-05)
Statins proved potential bone healing properties. Rosuvastatin is a synthetic, hydrophilic, potent and highly efficacious statin. In the current work, an attempt was investigated to develop, evaluate various bioerodible composite sponges enclosing rosuvastatin and explore their potential in augmenting bone
Sagar S Bachhav et al.
International journal of pharmaceutics, 532(1), 612-622 (2017-09-25)
The oral uptake of intact nanocarriers through Peyer's patches is an important uptake pathway. We report Rifampicin Lipid-Polymer hybrid nanoparticles (RIF-LIPOMER) using glyceryl monostearate as lipid and the mucoadhesive polymer, Gantrez, with the objective of balancing hydrophobicity and mucoadhesion for
Min Fang et al.
International journal of nanomedicine, 7, 5395-5404 (2012-10-24)
Curcumin has a variety of pharmacological effects. However, poor water solubility and low oral bioavailability limit its clinical utility. A delivery system for nanostructured lipid carriers has been reported to be a promising approach to enhancing the oral absorption of
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