Skip to Content
Merck
CN
All Photos(1)

Key Documents

View All Documentation

Safety Information

M157

Sigma-Aldrich

MEN-10,376

≥95% (HPLC), solid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C57H68N12O10
CAS Number:
135306-85-3
Molecular Weight:
1081.22
MDL number:
MFCD00144736
UNSPSC Code:
51111800
PubChem Substance ID:
24896670
NACRES:
NA.32

Quality Level

200

Assay

≥95% (HPLC)

form

solid

color

white

storage temp.

−20°C

SMILES string

CC(C)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(N)CC(O)=O)C(=O)NC(Cc4c[nH]c5ccccc45)C(=O)NC(Cc6c[nH]c7ccccc67)C(=O)NC(CCCCN)C(N)=O

InChI

1S/C57H68N12O10/c1-31(2)50(69-56(78)48(26-35-30-63-43-16-8-5-13-39(35)43)67-53(75)45(23-32-18-20-36(70)21-19-32)65-52(74)40(59)27-49(71)72)57(79)68-47(25-34-29-62-42-15-7-4-12-38(34)42)55(77)66-46(24-33-28-61-41-14-6-3-11-37(33)41)54(76)64-44(51(60)73)17-9-10-22-58/h3-8,11-16,18-21,28-31,40,44-48,50,61-63,70H,9-10,17,22-27,58-59H2,1-2H3,(H2,60,73)(H,64,76)(H,65,74)(H,66,77)(H,67,75)(H,68,79)(H,69,78)(H,71,72)

InChI key

QQHOFZNACVKNHK-UHFFFAOYSA-N

Gene Information

human ... TACR2(6865)

Looking for similar products? Visit Product Comparison Guide

Amino Acid Sequence

Asp-Tyr-Trp-Val-Trp-Trp-Lys-NH2

Biochem/physiol Actions

Potent and selective NK-2 tachykinin receptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBC6472V
041M1696V
041M1696
069K1725
074K11452

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Donatella Mutolo et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 295(1), R243-R251 (2008-05-16)
We have previously shown that ionotropic glutamate receptors in the caudal portion of the nucleus tractus solitarii (NTS), especially in the commissural NTS, play a prominent role in the mediation of tracheobronchial cough and that substance P potentiates this reflex.
Kyle M Baumbauer et al.
Behavioral neuroscience, 121(5), 1082-1094 (2007-10-03)
Previous research has demonstrated that spinally transected rats can acquire a prolonged flexion response to prevent the delivery of shock. However, rats that receive shock irrespective of leg position cannot learn to maintain the same response. The present experiments examined
Donatella Mutolo et al.
Journal of applied physiology (Bethesda, Md. : 1985), 109(4), 1002-1010 (2010-07-24)
We have previously shown that the caudal nucleus tractus solitarii is a site of action of some antitussive drugs and that the caudal ventral respiratory group (cVRG) region has a crucial role in determining both the expiratory and inspiratory components
Koichi Tan-No et al.
Brain research, 952(1), 7-14 (2002-10-05)
Intrathecal (i.t.) administration of big dynorphin (1-10 fmol), a prodynorphin-derived peptide consisting of dynorphin A and dynorphin B, to mice produced a characteristic behavioral response, the biting and/or licking of the hindpaw and the tail along with slight hindlimb scratching
O Löfgren et al.
Burns : journal of the International Society for Burn Injuries, 25(2), 125-129 (1999-04-20)
Recent studies have proposed that activation of the sensory nervous system after thermal injury induces the release of vasoactive neuropeptides, including tachykinins which contribute to the local inflammatory reaction as well as to the nociceptive transmission at the spinal cord
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service