L8135
Lysergol
Synonym(s):
9,10-Didehydro-6-methylergoline-8β-methanol
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About This Item
Empirical Formula (Hill Notation):
C16H18N2O
CAS Number:
Molecular Weight:
254.33
UNSPSC Code:
12352200
EC Number:
210-024-5
MDL number:
SMILES string
CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34
Other Notes
Supplied only to established institutions. Telephone orders not accepted.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Shinsuke Inuki et al.
The Journal of organic chemistry, 76(7), 2072-2083 (2011-03-03)
Enantioselective total synthesis of the biologically important indole alkaloids (+)-lysergol, (+)-isolysergol, and (+)-lysergic acid is described. Key features of these total synthesis include (1) a facile synthesis of a chiral 1,3-amino alcohol via the Pd(0)- and In(I)-mediated reductive coupling reaction
Shinsuke Inuki et al.
Organic letters, 10(22), 5239-5242 (2008-10-30)
Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key
E M Parker et al.
Journal of neurochemistry, 67(5), 2096-2103 (1996-11-01)
5-Hydroxytryptamine elicits its physiological effects by interacting with a diverse group of receptors. Two of these receptors, the 5-HT1D beta and the 5-HT1E receptors, are approximately 60% identical in the transmembrane domains that presumably form the ligand binding site yet
D Groó et al.
Polish journal of pharmacology and pharmacy, 40(6), 593-601 (1988-11-01)
Different ergot structures (lumilysergol and lysergol) were chlorinated or brominated in the position 2, and the development of antidopaminergic activity was studied. The tested 2-halo-lysergols exerted neuroleptic-like action indicated by the suppression of conditioned avoidance response (CAR), and other effects
S L Lodge-Ivey et al.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 18(4), 369-374 (2006-08-23)
Ergot alkaloids present in endophyte-infected tall fescue induce fescue toxicosis in livestock consuming the plant. The lysergic acid (LA) ring structure is a common moiety among the ergot alkaloids. Little is known about the bioavailability of LA because of limitations
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