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Safety Information

L8135

Sigma-Aldrich

Lysergol

Synonym(s):

9,10-Didehydro-6-methylergoline-8β-methanol

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About This Item

Empirical Formula (Hill Notation):
C16H18N2O
CAS Number:
Molecular Weight:
254.33
EC Number:
MDL number:
UNSPSC Code:
12352200

SMILES string

CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34

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Other Notes

Supplied only to established institutions. Telephone orders not accepted.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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V Kren et al.
Bioorganic & medicinal chemistry, 4(6), 869-876 (1996-06-01)
New glycosides derived from ergot alkaloids elymoclavine and DH-lysergol were synthesized by chemoenzymatic methods. beta-Glucosides were obtained either by chemical method or by transglycosylation (glycosidase from Aspergillus oryzae), lactosides were prepared by further extension of carbohydrate chain using beta-1,4-galactosyltransferase (bovine
D S Sveshnikov et al.
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, 33(5), 40-45 (1999-12-11)
Acute experiments with dogs showed that irritation of the sympathetic trunk in the thoracic cavity is more likely to amplify than inhibit duodenal contractions. This stimulating effect is better seen with alpha- and beta-adrenoreceptors blocked by phentolamine hydrochloride and inderal
Anupam Maurya et al.
Chemical biology & drug design, 81(4), 484-490 (2013-01-08)
Antibacterial activity of lysergol (1) and its semi-synthetic derivatives (2-14) and their synergy with the conventional antibiotic nalidixic acid (NA) against nalidixic acid-sensitive (NASEC) and nalidixic acid-resistant (NAREC) strains of Escherichia coli were evaluated. Lysergol (1) and derivatives (2-14) did
Anupam Maurya et al.
Biomedical chromatography : BMC, 26(9), 1096-1100 (2011-11-29)
A rapid, simple, sensitive, gradient and reproducible, reverse-phase high-performance liquid chromatographic method was developed for the quantitative estimation of bioactive alkaloids, lysergol and chanoclavine in the seeds of Ipomoea muricata. The clavine alkaloid, lysergol, is a bioenhancer for the drugs
S L Lodge-Ivey et al.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 18(4), 369-374 (2006-08-23)
Ergot alkaloids present in endophyte-infected tall fescue induce fescue toxicosis in livestock consuming the plant. The lysergic acid (LA) ring structure is a common moiety among the ergot alkaloids. Little is known about the bioavailability of LA because of limitations

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