L6654
Lacto-N-hexaose
from human milk, ≥95%
Synonym(s):
β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-(β-D-Gal-[1→4]-β-D-GlcNAc-[1→6])-β-D-Gal-(1→4)-D-Glc, LNH
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About This Item
Empirical Formula (Hill Notation):
C40H68N2O31
CAS Number:
Molecular Weight:
1072.96
MDL number:
UNSPSC Code:
12352201
Recommended Products
biological source
human milk
Assay
≥95%
storage temp.
2-8°C
SMILES string
CC(=O)NC1C(O)C(OC2OC(CO)C(O)C(O)C2O)C(CO)OC1OCC3OC(OC(C(O)CO)C(O)C(O)C=O)C(O)C(OC4OC(CO)C(O)C(OC5OC(CO)C(O)C(O)C5O)C4NC(C)=O)C3O
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V K Dua et al.
Journal of chromatography, 328, 259-269 (1985-06-28)
The branched hexasaccharide whose trivial name is lacto-N-hexaose (LNH) as well as a mono- and a difuco-derivative were isolated from human breast milk of a Lewis a positive donor by high-performance liquid chromatography (HPLC). Reversed-phase HPLC on C18 columns which
C Dumon et al.
Glycoconjugate journal, 18(6), 465-474 (2002-06-27)
We report here the in vivo production of type 2 fucosylated-N-acetyllactosamine oligosaccharides in Escherichia coli. Lacto-N-neofucopentaose Galbeta1-4GlcNAcbeta1-3Galbeta1-4(Fucalpha1-3)Glc, lacto-N-neodifucohexaose Galbeta1-4(Fucalpha1-3)Glc-NAcbeta1-3Galbeta1-4(Fucalpha1-3)Glc, and lacto-N-neodifucooctaose Galbeta1-4GlcNAcbeta1-3Galbeta1-4(Fucalpha1-3)GlcNAcbeta1-3Galbeta1-4(Fucalpha1-3)Glc were produced from lactose added in the culture medium. Two of them carry the Lewis X human antigen.
Marion Rohmer et al.
Analytical chemistry, 82(9), 3719-3726 (2010-04-15)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a widely used method in oligosaccharide analysis. Underivatized oligosaccharides are not well-suited for that purpose due to their low ionization efficiency; however, derivatization requires tedious sample purification steps which may lead
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