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Merck
CN

L6394

Lysozyme human

lyophilized powder, ≥100,000 units/mg protein

Synonym(s):

Mucopeptide N-acetylmuramoylhydrolase, Muramidase

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About This Item

CAS Number:
UNSPSC Code:
12352204
MDL number:
EC Number:
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form

lyophilized powder

specific activity

≥100,000 units/mg protein

composition

Protein, ~10% E1%/280

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... LYZ(4069)

Physical form

Lyophilized powder containing sodium phosphate and sodium chloride

Preparation Note

Derived from human milk

Other Notes

One unit will produce a ΔA450 of 0.001 per min at pH 6.24 at 25 °C, using a suspension of Micrococcus lysodeikticus as substrate, in a 2.6 mL reaction mixture (1 cm light path).


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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P F Zabrodskiĭ et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(11), 19-21 (2013-01-18)
It is established in experiments on noninbred rats that the use of imunofan (20 mg/kg daily) and polyoxidonium (150 mg/kg daily) for 7 days on the background of chronic intoxication with organophosphorus agent VX (0.01 LD50, single daily treatment for
Anne Derbise et al.
The Journal of infectious diseases, 207(10), 1535-1543 (2013-02-14)
Yersinia pestis (the plague bacillus) and its ancestor, Yersinia pseudotuberculosis (which causes self-limited bowel disease), encode putative homologues of the periplasmic lysozyme inhibitor Ivy and the membrane-bound lysozyme inhibitor MliC. The involvement of both inhibitors in virulence remains subject to
Mariela G Del Giudice et al.
Infection and immunity, 81(3), 956-964 (2013-01-16)
Secretion of proteins in Gram-negative bacteria is a high-energy-consuming process that requires translocation across two membranes and a periplasmic space composed of a mesh-like layer, the peptidoglycan. To achieve this, bacteria have evolved complex secretion systems that cross these barriers