L5908
Lacto-N-fucopentaose I
from human milk, ≥90% (HPAE/PAD)
Synonym(s):
α-L-Fuc (1→2)-β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-D-Glc, LNFP I
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About This Item
Empirical Formula (Hill Notation):
C32H55NO25
CAS Number:
Molecular Weight:
853.77
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
SMILES string
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](CO)O[C@@H](O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)[C@@H]4O)[C@@H]3NC(C)=O)[C@@H](O)[C@H](O)[C@@H]1O
biological source
human milk
assay
≥90% (HPAE/PAD)
storage temp.
2-8°C
Other Notes
Blood group H-active pentasaccharide.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Andrew Almond et al.
Biochemistry, 43(19), 5853-5863 (2004-05-12)
Fucosylated O- and N-linked glycans are essential recognition molecules in plants and animals. To understand how they impart their functions, through interactions with proteins, requires a detailed analysis of structure and dynamics, but this is presently lacking. In this study
S Lindenberg et al.
Journal of reproduction and fertility, 83(1), 149-158 (1988-05-01)
Seven oligosaccharides isolated from human milk were tested for their effect in an in-vitro model of mouse blastocyst adhesion and trophoblast outgrowth on endometrial epithelial monolayers. One compound, lacto-N-fucopentaose I (LNF I), produced a significant reduction in the percentage of
T Yamagata et al.
Biochemical and biophysical research communications, 181(3), 1004-1009 (1991-12-31)
Mouse embryos at implantation stage were stained successfully with lacto-N-fucopentaose I (LNF-I) bearing neoglycoprotein labeled with rhodamine synthesized by us for the first time. The fluorescent neoglycoproteins carrying LNF-II, -III, LND-I, or LNT failed to stain the embryos. The embryo
S Lindenberg
Danish medical bulletin, 38(5), 371-380 (1991-10-01)
6.1. Attachment and penetration of the uterine epithelium in the human: The present studies describe to our knowledge the only studies of human in vitro attachment of blastocysts to uterine epithelial monolayers. From these studies, using other mammalian species as
Carbohydrate binding properties of mouse embryos.
S Lindenberg et al.
Journal of reproduction and fertility, 89(2), 431-439 (1990-07-01)
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