L5751
L-Lysine dihydrochloride
≥98% (HPLC), suitable for ligand binding assays
Synonym(s):
(S)-2,6-Diaminohexanoic acid dihydrochloride
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About This Item
Linear Formula:
NH2(CH2)4CH(NH2)COOH · 2HCl
CAS Number:
Molecular Weight:
219.11
Beilstein:
4539715
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Product Name
L-Lysine dihydrochloride, ≥98% (HPLC)
Quality Level
Assay
≥98% (HPLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to faint yellow
mp
200-206 °C (lit.)
SMILES string
Cl[H].Cl[H].NCCCC[C@H](N)C(O)=O
InChI
1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m0../s1
InChI key
JBBURJFZIMRPCZ-XRIGFGBMSA-N
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Biochem/physiol Actions
L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Liying Yao et al.
PloS one, 11(2), e0149948-e0149948 (2016-02-24)
Myeloid-derived suppressor cells (MDSCs) are potent suppressors of T cell immunity in tumors and inflammatory diseases. They are identified by surface expression of CD11b+Gr1+ in mice, and CD11b+Gr1+ cells accumulate in the livers of obese mice. However, many myeloid cells
Zachery R Jarrell et al.
Aging, 12(13), 13555-13570 (2020-06-20)
Acylcarnitines transport fatty acids into mitochondria and are essential for β-oxidation and energy metabolism. Decreased mitochondrial activity results in increased plasma acylcarnitines, and increased acylcarnitines activate proinflammatory signaling and associate with age-related disease. Changes in acylcarnitines associated with healthy aging
Xiu-Min Chen et al.
Journal of agricultural and food chemistry, 59(20), 11294-11303 (2011-09-23)
We investigated the antioxidant and anti-inflammatory activities of both crude and ultrafiltrated Maillard reaction (MR) products (MRPs) derived from sugar-amino acid MR models, comprising fructose (Fru), glucose (Glu) or ribose (Rib) reacted with glycine (Gly) or lysine (Lys), respectively. Crude
Gong Zhang et al.
Journal of agricultural and food chemistry, 59(22), 12037-12046 (2011-10-11)
A sensitive and reliable LC-(ESI)MS/MS method was developed and validated for the simultaneous analysis of five common advanced glycation endproducts (AGEs) after enzymatic digestion in raw and roasted almonds. AGEs included carboxymethyl-lysine (CML), carboxyethyl-lysine (CEL), pyralline (Pyr), argpyrimidine (Arg-p), and
Stefan W Vetter et al.
Clinica chimica acta; international journal of clinical chemistry, 412(23-24), 2105-2116 (2011-08-13)
Serum protein glycation and formation of advanced glycation endproducts (AGE) correlates with diabetic complications. Highly AGE-modified albumin is frequently used to study the biochemical and cellular activities of AGE-proteins. However, moderately modified albumin samples are expected to be (patho)physiologically more
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