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Merck
CN

L5125

N-Lauroylsarcosine sodium salt

≥94%

Synonym(s):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12352107
NACRES:
NA.32
PubChem Substance ID:
57654330
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
MFCD00042728

Key Documents

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Product Name

N-Lauroylsarcosine sodium salt, ≥94%

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

description

anionic

assay

≥94%

form

powder

mol wt

micellar avg mol wt 600
average mol wt 600

aggregation number

2

technique(s)

oligo synthesis: suitable

CMC

14.6 mM (20-25°C)

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

density

1,14 g/cm3 at 20 °C (1,14 g/cm3 at 20 °C)

Quality Level

200

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Application

N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans.

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Other Notes

Anionic surfactant.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000516344
0000516345
0000516345
0000516344
0000496293

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P W Caufield et al.
Journal of clinical microbiology, 27(2), 274-278 (1989-02-01)
Attempts to study the acquisition, transmission, and other aspects of the natural history of Streptococcus mutans infections in humans have been hampered by limitations and inconsistencies in methods by which phenotypic characteristics of individual isolates are examined. Because most mutans
N S Andrade et al.
Genetics and molecular research : GMR, 7(4), 1414-1421 (2009-02-19)
Baccharis dracunculifolia De Candole (DC) (Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly valued Brazilian green propolis. As no
Sarah Houben et al.
Frontiers in molecular neuroscience, 13, 106-106 (2020-08-09)
Alzheimer's disease (AD) is characterized by the accumulation in the brain of intraneuronal aggregates of abnormally and hyperphosphorylated tau proteins and of extracellular deposits of amyloid-β surrounded by dystrophic neurites. Numerous experimental models have shown that tau pathology develops in
S Roy et al.
Antimicrobial agents and chemotherapy, 45(6), 1671-1681 (2001-05-17)
The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
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