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Merck
CN

L5000

N-Lauroylsarcosine, neat

≥95%

Synonym(s):

N-Dodecanoyl-N-methylglycine, Sarkosyl L

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COOH
CAS Number:
97-78-9
Molecular Weight:
271.40
NACRES:
NA.21
PubChem Substance ID:
24896382
UNSPSC Code:
12161900
EC Number:
202-608-3
MDL number:
MFCD00021749

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InChI key

BACYUWVYYTXETD-UHFFFAOYSA-N

InChI

1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)

SMILES string

CCCCCCCCCCCC(=O)N(C)CC(O)=O

description

anionic

assay

≥95%

mol wt

average mol wt 600

aggregation number

2

CMC

14.6

Quality Level

200

Related Categories

General description

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Physical form

May be liquid at room temperature

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCJ7006
MKCJ5348
MKCD5419
MKBL7505V
MKBC8483V

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Manfeng Zhang et al.
PLoS biology, 18(6), e3000748-e3000748 (2020-06-20)
Curli play critical roles in biofilm formation, host cell adhesion, and colonization of inert surfaces in many Enterobacteriaceae. In Escherichia coli, curli biogenesis requires 7 curli-specific gene (csg) products-CsgA through G-working in concert. Of them, CsgG and CsgF are 2
Victoria C de Leeuw et al.
Reproductive toxicology (Elmsford, N.Y.), 98, 107-116 (2020-09-16)
Human embryonic stem cell neuronal differentiation models provide promising in vitro tools for the prediction of developmental neurotoxicity of chemicals. Such models mimic essential elements of human relevant neuronal development, including the differentiation of a variety of brain cell types
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 286(21), 18664-18672 (2011-04-02)
The transactivation response element (TAR) DNA-binding protein-43 (TDP-43) is a nuclear protein that normally regulates transcription and splicing. Abnormal accumulation of insoluble inclusions containing TDP-43 has been recently reported in the affected tissues of amyotrophic lateral sclerosis (ALS) patients. Here
Kunie Ando et al.
The American journal of pathology, 178(2), 803-816 (2011-02-02)
Many models of human tauopathies have been generated in mice by expression of a human mutant tau with maintained expression of mouse endogenous tau. Because murine tau might interfere with the toxic effects of human mutant tau, we generated a
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
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Product Information Sheet - L5000

Product Information Sheet

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