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Safety Information

L1516

Sigma-Aldrich

Lectin from Wisteria floribunda

buffered aqueous solution, biotin conjugate

Synonym(s):

Wisteria floribunda agglutinin, WFA

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About This Item

MDL number:
MFCD00166187
UNSPSC Code:
12352202
NACRES:
NA.32

conjugate

biotin conjugate

Quality Level

200

form

buffered aqueous solution

packaging

pkg of 2 mg active conjugate

storage temp.

2-8°C

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Biochem/physiol Actions

WFA is not blood group specific, but has an affinity for N-acetyl-D-galactosamine.

Packaging

Package size based on active conjugate content

Preparation Note

Protein is biotinylated utilizing aminocaproyl spacer.

Analysis Note

Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of human blood group A erythrocytes after 1 hr incubation at 25 °C.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

动植物源性产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000424287
0000424287
0000401051
0000391282
0000302585

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Carly M Drzewiecki et al.
Brain structure & function, 225(8), 2495-2507 (2020-09-12)
The prefrontal cortex (PFC) is a late developing region of the cortex, and its protracted maturation during adolescence may confer a period of plasticity. Closure of critical, or sensitive, periods in sensory cortices coincides with perineuronal net (PNN) expression, leading
Marie Mennesson et al.
eNeuro, 7(4) (2020-08-14)
NETO2 is an auxiliary subunit for kainate-type glutamate receptors that mediate normal cued fear expression and extinction. Since the amygdala is critical for these functions, we asked whether Neto2 -/- mice have compromised amygdala function. We measured the abundance of
Tania M Fowke et al.
Scientific reports, 7, 44135-44135 (2017-03-14)
Hyaluronan is a linear glycosaminoglycan that forms the backbone of perineuronal nets around neurons in the cerebral cortex. However, it remains controversial whether neurons are capable of independent hyaluronan synthesis. Herein, we examined the expression of hyaluronan and hyaluronan synthases
Thiri W Lin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(10), 2533-2550 (2018-02-13)
GABA signaling has been implicated in neural development; however, in vivo genetic evidence is missing because mutant mice lacking GABA activity die prematurely. Here, we studied synapse development by ablating vesicular GABA transporter (Vgat) in ErbB4+ interneurons. We show that
Jenni Kyyriäinen et al.
Epilepsy research, 151, 67-74 (2019-03-06)
Extracellular proteolysis initiated by the binding of urokinase-type plasminogen activator (uPA) to its receptor (uPAR) regulates the development of inhibitory neuronal circuits in the cerebral cortex and tissue remodeling after epileptogenic brain injury. To study the function of different components
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