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Safety Information

L1417

Sigma-Aldrich

15(S)-Latanoprost solution

≥95%

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Synonym(s):
(5Z,9α,11α,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate isopropyl ester
Empirical Formula (Hill Notation):
C26H40O5
Molecular Weight:
432.59
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥95%

form

liquid

concentration

10 mg/mL in methyl acetate

storage temp.

−20°C

SMILES string

CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@H](O)CCc2ccccc2

InChI

1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22-,23-,24+,25-/m1/s1

InChI key

GGXICVAJURFBLW-SCTZCWPJSA-N

Linkage

15(S)-Latanoprost is the less active C-15 isomer of latanoprost where the C-15 hydroxyl group is inverted relative to its natural (α) position in a prostaglandin such as PGF. The 15(S)-isomer of latanoprost occurs as an impurity of between 0.1 and 1% in most commercial preparations of latanoprost.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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