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L0376

Sigma-Aldrich

L-Leucine β-naphthylamide hydrochloride

leucine aminopeptidase substrate

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Synonym(s):
L-Leucine-2-naphthylamide hydrochloride
Empirical Formula (Hill Notation):
C16H20N2O · HCl
CAS Number:
893-36-7
Molecular Weight:
292.80
Beilstein:
3918167
EC Number:
212-970-4
MDL number:
MFCD00034972
UNSPSC Code:
12352204
eCl@ss:
32160406
PubChem Substance ID:
24896251
NACRES:
NA.32

Quality Level

200

Assay

≥98% (TLC)

form

powder

solubility

H2O: soluble

storage temp.

−20°C

SMILES string

Cl[H].CC(C)C[C@H](N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C16H20N2O.ClH/c1-11(2)9-15(17)16(19)18-14-8-7-12-5-3-4-6-13(12)10-14;/h3-8,10-11,15H,9,17H2,1-2H3,(H,18,19);1H/t15-;/m0./s1

InChI key

HTHKKWZMEVJWQF-RSAXXLAASA-N

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Application

Substrate for leucine aminopeptidase determination in colorimetric and histochemical procedures.

Quality

Very low free β-naphthylamine.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M Niinobe et al.
Journal of biochemistry, 87(1), 195-203 (1980-01-01)
Aminopeptidase and arylamidase from human liver were purified 1,580- and 1,130-fold, respectively, by ammonium sulfate fractionation, TEAE-cellulose and hydroxylapatite column chromatographies, and Sephadex G-200 gel filtration. The purified preparations appeared to be homogeneous on polyacrylamide gel electrophoresis. The molecular weights

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