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I9148

Sigma-Aldrich

Sodium iodoacetate

≥98%, BioUltra

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Synonym(s):
Iodoacetic acid sodium salt
Linear Formula:
ICH2COONa
CAS Number:
305-53-3
Molecular Weight:
207.93
Beilstein:
4009322
EC Number:
206-165-7
MDL number:
MFCD00002686
UNSPSC Code:
12352202
PubChem Substance ID:
24896151
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

product line

BioUltra

Assay

≥98%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

208 °C (dec.) (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.001%
Fe: ≤0.0005%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

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Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H301,H314

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

406.4 °F

Flash Point(C)

208 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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