I7013
Imidazole-4-acetic acid sodium salt
Synonym(s):
I4AA
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About This Item
Empirical Formula (Hill Notation):
C5H5N2NaO2
CAS Number:
Molecular Weight:
148.10
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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storage temp.
2-8°C
SMILES string
[Na+].[O-]C(=O)Cc1c[nH]cn1
InChI
1S/C5H6N2O2.Na/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);/q;+1/p-1
InChI key
JDDRCOTZMQIPOQ-UHFFFAOYSA-M
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Biochem/physiol Actions
Competitive antagonist at GABAC receptors.
Features and Benefits
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Greg T Cantin et al.
Analytical chemistry, 79(12), 4666-4673 (2007-05-26)
An automated online multidimensional liquid chromatography system coupled to ESI-based tandem mass spectrometry was used to assess the effectiveness of TiO2 in the enrichment of phosphopeptides from tryptic digests of protein mixtures. By monitoring the enrichment of phosphopeptides, an optimized
Zihao Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(37), 13793-13798 (2008-09-10)
Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via its interplay with phosphorylation.
Terrence M Black et al.
Journal of proteome research, 6(6), 2269-2276 (2007-05-03)
Advances in analytical techniques, specifically in mass spectrometry, have allowed for both facile protein identification and routine sequencing of proteins at increased sensitivity levels. Protein modifications present additional challenges because they occur at low stoichiometries and often change the analytical
Xumin Zhang et al.
Molecular & cellular proteomics : MCP, 6(11), 2032-2042 (2007-08-07)
A new method for enrichment of phosphopeptides in complex mixtures derived by proteolytic digestion of biological samples has been developed. The method is based on calcium phosphate precipitation of the phosphopeptides prior to further enrichment with established affinity enrichment methods.
Jan Sedzik et al.
Protein expression and purification, 26(3), 368-377 (2002-12-04)
The preparation of a pure and homogeneous protein sample at proper concentration is a prerequisite for success when attempting their crystallization for structural determination. The detergents suitable for solubilization particularly of membrane proteins are not always the best for crystallization.
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