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I5763

Sigma-Aldrich

Indophenol

Powder

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Synonym(s):
Phenolindophenol
Empirical Formula (Hill Notation):
C12H9NO2
CAS Number:
Molecular Weight:
199.21
Beilstein:
2095656
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

color

dark green to black

mp

>300 °C (lit.)

solubility

1 M NaOH: 10 mg/mL, clear, blue to very deep blue

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1)N=C2C=CC(=O)C=C2

InChI

1S/C12H9NO2/c14-11-5-1-9(2-6-11)13-10-3-7-12(15)8-4-10/h1-8,14H

InChI key

RSAZYXZUJROYKR-UHFFFAOYSA-N

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General description

Indophenol is used in hair dyes, redox materials, lubricants, liquid crystal displays, biosensor and fuel cells. It is toxic to fishes and is implicated in environmental pollution.
Indophenol method is common for the determination of ammonia. The reaction gives a blue product, which is measured spectrophotometrically.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Handbook of Acid-Base Indicators (2007)
Marczenko Z and Balcerzak M
Separation, Preconcentration and Spectrophotometry in Inorganic Analysis (2000)
Mark G Devlin et al.
European journal of pharmacology, 498(1-3), 59-69 (2004-09-15)
The effect of ligand pretreatment on human 5-hydroxytryptamine2C (5-HT2C) receptors was examined in CHO cells expressing high (CHO-1C7; 67+/-3 pmol/mg) or low (CHO-1C19; 72+/-10 fmol/mg) levels of the receptor. Seventy-two hours pretreatment of CHO-1C7 cells with various ligands did not
Sonia Senra-Ferreiro et al.
Talanta, 85(3), 1448-1452 (2011-08-03)
A miniaturized method based on liquid-phase microextraction (LPME) in combination with microvolume UV-vis spectrophotometry for monitoring ammonia in waters is proposed. The methodology is based on the extraction of the ion pair formed between the blue indophenol obtained according to
Christen M Cormier et al.
Journal of neurotrauma, 27(10), 1805-1818 (2010-08-12)
Autonomic dysreflexia consistently develops in patients and in rats after severe upper thoracic spinal cord injury (SCI) as a result of exaggerated spinal sympathetic excitation. In this study we induced episodic hypertension in rats after varying degrees of SCI severity

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