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I5505

Sigma-Aldrich

Indoxyl phosphate disodium salt

crystalline

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Synonym(s):
3-Indoxyl phosphate disodium salt, Disodium 3-indoxyl phosphate
Empirical Formula (Hill Notation):
C8H6NNa2O4P
CAS Number:
Molecular Weight:
257.09
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

Assay

≥94% (HPLC)

Quality Level

form

crystalline

solubility

water: 5 mg/mL, clear to slightly hazy

storage temp.

−20°C

SMILES string

[Na+].[Na+].[O-]P([O-])(=O)Oc1c[nH]c2ccccc12

InChI

1S/C8H8NO4P.2Na/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;;/h1-5,9H,(H2,10,11,12);;/q;2*+1/p-2

InChI key

WCSKWBKPKXJWEG-UHFFFAOYSA-L

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Substrates

Histochemical substrate for alkaline phosphatase.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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T Kanno et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 90(4), 782-788 (1993-04-01)
We assessed a clinical usefulness of JSCC (Japan Society of Clinical Chemistry) recommended method for the measurement of serum alkaline phosphatase. The recommended method is completely correlated both in the liver-bone and intestine isoenzymes with Kind-King method recommended by the
Pablo Fanjul-Bolado et al.
Analytical chemistry, 79(14), 5272-5277 (2007-06-16)
Alkaline phosphatase (AP) is one of the most used enzymatic labels for the development of ELISAs, immunosensors, DNA hybridization assays, etc. This enzyme catalyzes the dephosphorylation of a substrate into a detectable product usually quantified by optical or electrochemical measurements.
Chemiluminescent enzyme immunoassay of prostate-specific antigen based on indoxyl phosphate substrate.
S Albrecht et al.
Clinical chemistry, 40(10), 1970-1971 (1994-10-01)
David Hernández-Santos et al.
Analytical chemistry, 76(23), 6887-6893 (2004-12-02)
Voltammetric enzyme genosensors on streptavidin-modified screen-printed carbon electrodes (SPCEs) for the detection of virulence nucleic acid determinants of pneumolysin and autolysin genes, exclusively present on the genome of the human pathogen Streptococcus pneumoniae, were described. Alkaline phosphatase (AP) and 3-indoxyl
Kinetics of the oxidation of indoxyl liberated from indoxyl phosphate by kidney alkaline phosphatase.
S Kirkeby et al.
Basic and applied histochemistry, 26(2), 71-78 (1982-01-01)

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