I3653
Anti-Interferon β antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-IFN-β
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biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
western blot: 0.1-2.0 μg/mL
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IFNB1(3456)
General description
Type I interferons are proteins produced in response to inducers like viral infection and can be divided into α and β subtypes. IFN-β provokes high antiproliferation response in certain cells like embryonal carcinoma, melanoma and melanocytes. It also has high potency in treatment of multiple sclerosis and certain cancers. Anti-interferon β antibody can be used in western blot. Goat anti-interferon β antibody reacts specifically with human interferon-β and has shown no cross reactivity with recombinant human interferon-γ.
Specificity
The antibody will neutralize the biological activity of recombinant human IFN-β. It will not block the biological activity of recombinant human IFN-α or IFN-γ.
Immunogen
recombinant human IFN-β, expressed in Escherichia coli.
Application
Anti-interferon β antibody can be used in immunoblotting. It can also be used to neutralize the bioactivity of recombinant human interferon-β.
Physical form
Lyophilized from a solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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P Belhumeur et al.
Molecular and cellular biology, 13(5), 2846-2857 (1993-05-01)
In the current study, we have addressed the role of interferons (IFNs) in controlling the differentiation of pluripotent P19 embryonal carcinoma (EC) cells. Blocking IFN activity in the culture medium of differentiating cells with antibodies leads to a strong decrease
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