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Key Documents

Safety Information

I3642

Sigma-Aldrich

Monoclonal Anti-Interleukin-1β antibody produced in mouse

clone 8516.311, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-IL-1β

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0.5 MG
¥1,459.47

¥1,459.47

List Price¥4,864.92Save 70%

Available to ship on2025年4月16日Details

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0.5 MG
¥1,459.47

About This Item

MDL number:
MFCD00162514
UNSPSC Code:
51111800
NACRES:
NA.41

¥1,459.47

List Price¥4,864.92Save 70%

Available to ship on2025年4月16日Details

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8516.311, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: suitable
immunohistochemistry: 8-25 μg/mL using human PBMC′s
neutralization: suitable
western blot: 1 μg/mL

isotype

IgG1

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抗-白介素1单克隆抗体β 小鼠抗 clone 8516.311, purified immunoglobulin, lyophilized powder

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抗-白介素1单克隆抗体β 小鼠抗

Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse clone 70625.111, purified immunoglobulin, lyophilized powder

I4028

Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse

Monoclonal Anti-IL1B antibody produced in mouse clone 2A8, purified immunoglobulin, buffered aqueous solution

WH0003553M1

Monoclonal Anti-IL1B antibody produced in mouse

Sigma-Aldrich

I7534

Monoclonal Anti-Interleukin-1α antibody produced in mouse

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

Gene Information

human ... IL1B(3553)

Gene Information

human ... IL18R1(8809)

Gene Information

human ... IL1B(3553)

Gene Information

human ... IL1A(3552)

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

clone

8516.311, monoclonal

clone

70625.111, monoclonal

clone

2A8, monoclonal

clone

4414, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

Specificity

The antibody will neutralize the biological activity of recombinant human IL-1β. It will not neutralize the activity of recombinant human IL-α, recombinant mouse IL-1α, or recombinant mouse IL-1β. When immobilized on a microplate, this antibody will capture both recombinant as well as natural human IL-1β. In immunoblotting, the antibody shows ~25% cross-reactivity with recombinant rat IL-1β and <5% cross-reactivity with recombinant mouse IL-1β and recombinant porcine IL-1β. Additionally, in immunoblotting, the antibody exhibits no cross-reactivity with recombinant mouse IL-α, recombinant human IL-1ra, recombinant mouse IL-1ra, or recombinant rat IL-1α.

Immunogen

purifed, E. coli-derived, recombinant human IL-1β.

Application

May used in immunoblotting, immunohistochemistry, ELISA, and neutralization assays

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Preparation Note

Monoclonal Anti-Interleukin-1(IL-1) (mouse IgG1 isotype) is purified from a mouse hybridoma utilizing Protein A affinity chromatography.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000340371
    0000323792
    0000340371
    0000323792
    0000278609

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