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I3386

Imidazole hydrochloride

Name: Imidazole hydrochloride
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₃H₄N₂ · HCl

CAS Number:

1467-16-9

Molecular Weight:

104.54

Beilstein:

3678283

MDL number:

MFCD00012695

UNSPSC Code:

12161700

eCl@ss:

39161001

PubChem Substance ID:

24896034

NACRES:

NA.25

Assay

≥98% (TLC)
≥98.5% (perchloric acid titration)

Quality Level

200

form

powder

pH

9.0-10.0

mp

158-161 °C (lit.)

solubility

methanol: 50 mg/mL, clear, colorless to faintly yellow

application(s)

diagnostic assay manufacturing

SMILES string

Cl.c1c[nH]cn1

InChI

1S/C3H4N2.ClH/c1-2-5-3-4-1;/h1-3H,(H,4,5);1H

InChI key

JDIIGWSSTNUWGK-UHFFFAOYSA-N

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Biological Buffers

Application

Imidazole hydrochloride has been used:

in double immunohistochemistry
to determine the activity of octopine dehydrogenase (ODH) in Mytilus galloprovincialis
to study the cytoskeletal features during in vitro fertilization after intracytoplasmic sperm injection (ICSI) among humans
as a reagent in the synthesis of a probe for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene expression in rodents

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Precautionary Statements

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Biochemical responses of the marine mussel Mytilus galloprovincialis to petrochemical environmental contamination along the North-western coast of Portugal

Lima I, et al.

Chemosphere, 66(7), 1230-1242 (2007)

Exploring the cytoskeleton during intracytoplasmic sperm injection in humans

Microinjection: Methods and Applications, 189-206 (2009)

The alpha4beta2 nicotine acetylcholine receptor agonist is pronicline induces c-Fos expression in selective regions of the rat forebrain

Jacobsen J, et al.

Neuroscience Letters, 515(1), 7-11 (2012)

Enhanced production of 2,3-butanediol by engineered Saccharomyces cerevisiae through fine-tuning of pyruvate decarboxylase and NADH oxidase activities.

Jin-Woo Kim et al.

Biotechnology for biofuels, 9, 265-265 (2016-12-19)

2,3-Butanediol (2,3-BD) is a promising compound for various applications in chemical, cosmetic, and agricultural industries. Pyruvate decarboxylase (Pdc)-deficient Saccharomyces cerevisiae is an attractive host strain for producing 2,3-BD because a large amount of pyruvate could be shunted to 2,3-BD production

Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI.

Bar-Shir A

Nature Protocols, 8(12), 2380-2380 (2013)

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