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About This Item
Empirical Formula (Hill Notation):
C6H8N2O8
CAS Number:
Molecular Weight:
236.14
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
form
powder
contains
~60% lactose
color
white
solubility
organic solvents: soluble (alcohol, acetone and ether)
SMILES string
[H][C@@]1([C@@]([H])(O[N+]([O-])=O)CO2)[C@@]2([H])[C@]([H])(O[N+]([O-])=O)CO1
InChI
1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2
InChI key
MOYKHGMNXAOIAT-UHFFFAOYSA-N
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Biochem/physiol Actions
Nitric oxide (NO) donor and nitrovasodilator. Induces stimulation of corpus mucin biosynthesis in vivo. Used to study the role of nitric oxide in the control of cell growth.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Desen. Expl. 3
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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S Fujii et al.
The American journal of physiology, 274(5 Pt 1), G857-G862 (1998-06-05)
Recently, in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging have been widely used to investigate free radical distribution and metabolism in tissues, organs, and whole body of small animals. Endogenous nitric oxide (NO) is an attractive target of this
Benjamin Medalion et al.
The Journal of thoracic and cardiovascular surgery, 150(3), 607-612 (2015-07-21)
Bilateral internal thoracic artery grafting in elderly patients is controversial. We compared the outcome of bilateral internal thoracic artery grafting with that of single internal thoracic artery and saphenous vein and radial artery conduits in these patients. Patients aged 70 years
C Sciorati et al.
British journal of pharmacology, 122(4), 687-697 (1998-01-10)
1. The role of nitric oxide (NO) in the control of cell growth is controversial since both stimulation and (more often) inhibition have been demonstrated in various cell types. In order to reinvestigate the problem and identify the sites of
Maria Grazia D'Angelo et al.
Pharmacological research, 65(4), 472-479 (2012-02-07)
This open-label, single centre pilot study was designed to evaluate safety and tolerability of the combination of the drugs isosorbide dinitrate, a nitric oxide donor, and ibuprofen, a non steroid anti-inflammatory drug, in a cohort of adult dystrophic patients (Duchenne
S Weber et al.
Archives des maladies du coeur et des vaisseaux, 85(1), 59-65 (1992-01-01)
The eventuality of tolerance was assessed in 19 patients with unstable angina treated by continuous intravenous infusion of 50 micrograms/min of isosorbide trinitrate (ISDN) in association with heparin and betablocker therapy. The tolerance phenomenon was evaluated by the hypotension produced
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