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Safety Information

I141

Sigma-Aldrich

Intralipid

emulsion, lipid emulsion

Synonym(s):

Phospholipid stabilized soybean oil

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About This Item

CAS Number:
68890-65-3
MDL number:
MFCD00287215
UNSPSC Code:
51111800
NACRES:
NA.77

product name

Intralipid, 20%, emulsion

form

emulsion

Quality Level

200

concentration

20%

color

white

storage temp.

2-8°C

Application

Intralipid has been used:
  • for testing its optical properties to be used as scattering medium for tissue phantom generation
  • as a component of agarose gel phantom to reduce scatter coefficients and background absorption
  • in infusion into mice in hyperinsulinemic-euglycemic clamps studies to evaluate its effect on nonesterified free fatty acids (NEFA) circulation

Biochem/physiol Actions

Intralipid is a lipid emulsion comprising soybean oil. It favors proinflammatory cytokines production and is recommended for the treatment of immune-mediated pregnancy and implantation failure. In parenteral nutrition, intralipid is the source of fats. It elicits protection in heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. Intralipid is an effective alternative for intravenous immunoglobulin and improves bioavailability of platinum based anti-cancer drugs.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Can Product I141, Intralipid, be used in cell culture?

    We have not tested this product for cell culture application. An article by Per Oscarsson, A., et al., Acta Anaesthesiol. Scand. 45, 1215-1220 (2001), used Intralipid in cell culture with primary cultured rat neurons at 1.0 mg/mL for 20 minutes.

  6. How should Product I141, Intralipid, be stored?

    This product should be stored tightly sealed at 2-8°C.

  7. What are the components of Product I141, Intralipid?

    This Intralipid is made up of 20% soybean oil, 1.2% egg yolk phospholipids and 2.25% glycerin; the remainder is water.  

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice
Xu W, et al.
Molecular and Cellular Endocrinology, 482(22), 1-10 (2019)
Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A
Li J, et al.
Anesthesiology, 117(4), 836-846 (2012)
Birgitta I Zielbauer et al.
Journal of colloid and interface science, 529, 197-204 (2018-06-13)
Oleosomes are stabilized by a complex outer phospholipid-protein-layer. To improve understanding of its structure and stabilization mechanism, this shell has to be studied in extracellular native conditions. This should be possible by SANS using contrast variation. Oleosomes are expected to
Lisa R Beutler et al.
eLife, 9 (2020-07-29)
Body weight is regulated by interoceptive neural circuits that track energy need, but how the activity of these circuits is altered in obesity remains poorly understood. Here we describe the in vivo dynamics of hunger-promoting AgRP neurons during the development
Benedict Mc Larney et al.
Journal of biophotonics, 12(6), e201800387-e201800387 (2019-02-01)
Accurate image reconstruction in volumetric optoacoustic tomography implies the efficient generation and collection of ultrasound signals around the imaged object. Non-uniform delivery of the excitation light is a common problem in optoacoustic imaging often leading to a diminished field of
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