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Key Documents

Safety Information

HPA038109

Sigma-Aldrich

Anti-FAM13A antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-FAM13A1, Anti-Family with sequence similarity 13, member A, Anti-KIAA0914

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Select a Size

10 G
¥2,079.15
50 G
¥8,202.21
250 G
¥27,811.75

¥2,079.15

Available to ship on2025年4月27日Details

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10 G
¥2,079.15
50 G
¥8,202.21
250 G
¥27,811.75

About This Item

UNSPSC Code:
12352203
Human Protein Atlas Number:
HPA038109
NACRES:
NA.41

¥2,079.15

Available to ship on2025年4月27日Details

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:500-1:1000

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1-庚烷磺酸钠 一水合物 suitable for ion pair chromatography, LiChropur™, ≥99.0% (T)

51832

1-庚烷磺酸钠 一水合物

assay

≥99.0% (T)

assay

≥99.0% (T)

assay

≥97.0% (T)

assay

≥99.0% (T)

form

sheet

form

sheet

form

sheet

form

solid

suitability

corresponds to standard for RP gradient test, corresponds to standard for filter test

suitability

-

suitability

-

suitability

corresponds to standard for RP gradient test, corresponds to standard for filter test

technique(s)

ion pair chromatography: suitable

technique(s)

ion pair chromatography: suitable

technique(s)

-

technique(s)

ion pair chromatography: suitable

mol wt

234.29 g/mol

mol wt

234.29 g/mol

mol wt

-

mol wt

220.26 g/mol

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

-

General description

Family with sequence similarity 13 member A (FAM13A), also known as FAM13A1, is encoded by the gene mapped to human chromosome 4q22.1.[1] The encoded protein contains Rho GTPase-activating protein (Rho-GAP) domain.

Immunogen

family with sequence similarity 13, member A recombinant protein epitope signature tag (PrEST)

Application

Anti-FAM13A antibody produced in rabbit has been used in immunohistochemistry and western blot analysis.[1][2]
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem/physiol Actions

Family with sequence similarity 13 member A (FAM13A) plays a vital role in signal transduction. Mutation in the gene is linked with chronic obstructive pulmonary disease (COPD). The encoded protein can regulate the stability of β-catenin. In addition, it also regulates growth and progression of non-small cell lung cancer (NSCLC).

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

Linkage

Corresponding Antigen APREST79751

Physical form

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    R34975

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    Find documentation for the products that you have recently purchased in the Document Library.

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    FAM13A is associated with non-small cell lung cancer (NSCLC) progression and controls tumor cell proliferation and survival.
    Eisenhut F
    Oncoimmunology, 6 (2016)
    FAM13A locus in COPD is independently associated with lung cancer - evidence of a molecular genetic link between COPD and lung cancer.
    Young RP
    The Application of Clinical Genetics, 4, 1-10 (2010)
    A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of ?-Catenin.
    Jiang Z
    American Journal of Respiratory and Critical Care Medicine, 194, 185-197 (2016)
    Variants in FAM13A are associated with chronic obstructive pulmonary disease.
    Cho MH
    Nature Genetics, 42, 200-202 (2010)
    Jinyuan Zhu et al.
    Respiratory research, 22(1), 192-192 (2021-07-03)
    To explore the role of family with sequence similarity 13 member A (FAM13A) in TGF-β1-induced EMT in the small airway epithelium of patients with chronic obstructive pulmonary disease (COPD). Small airway wall thickness and protein levels of airway remodeling markers
    View All Related Papers

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