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Merck
CN

HMC0003

MISSION® miRNA, Negative Control 2

Sequence from Caenorhabditis elegans with no homology to human gene sequences

Synonym(s):

Mature Sequence: CGGUACGAUCGCGGCGGGAUAUC

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About This Item

NACRES:
NA.51
UNSPSC Code:
12352200
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product line

MISSION®

form

liquid

storage temp.

−20°C

General description

MISSION® miRNA Negative Controls are an essential component to any miRNA experiment. Using a negative control allows the researcher to create a baseline for mRNA knockdown effciency. The negative controls have been carefully selected, and have no known homology to known human gene sequences. Negative Control 2 is based upon a Caenorhabditis elegans sequence.

Application

MISSION® miRNA, Negative Control 2 has been used as a negative control for miRNA transfections.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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miRepress: modelling gene expression regulation by microRNA with non-conventional binding sites.
Ghosal S et al.
Scientific Reports, 6, 22334-22334 (2016)
Genome-Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR-140-5p.
Barter MJ et al.
Stem Cells, 33, 3266-3266 (2015)
NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells.
Chuang AY et al.
Inflammatory bowel diseases, 20, 126-126 (2014)
Utpreksha Vaish et al.
Scientific reports, 9(1), 10079-10079 (2019-07-14)
Translation of genes is regulated by many factors including microRNAs (miRNAs). miRNA profiling of lesional and non-lesional epidermal RNA from 18 vitiligo patients revealed significant upregulation of 29 miRNAs in the lesional epidermis, of which 6 miRNAs were transfected in
Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192
Sun, L. et al.
The Journal of Physiology, 3, 364-377 (2011)

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