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H6750

Hippuryl-Lys

Name: Hippuryl-Lys
Brand: SIGMA

Synonym(s):

N-Benzoyl-Gly-Lys

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₁N₃O₄

CAS Number:

740-63-6

Molecular Weight:

307.34

NACRES:

NA.32

PubChem Substance ID:

24895759

UNSPSC Code:

12352204

MDL number:

MFCD00038208

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Properties

assay

≥98% (TLC)

Quality Level

200

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCCCCC(NC(=O)CNC(=O)c1ccccc1)C(O)=O

InChI

1S/C15H21N3O4/c16-9-5-4-8-12(15(21)22)18-13(19)10-17-14(20)11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,16H2,(H,17,20)(H,18,19)(H,21,22)

InChI key

LRCZLURYHGISRZ-UHFFFAOYSA-N

Description

General description

Substrate for carboxypeptidase B and carboxypeptidase N.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Rapid assay of human plasma carboxypeptidase N by high-performance liquid chromatographic separation of hippuryl-lysine and its product.

F Marceau et al.

Journal of chromatography, 266, 173-177 (1983-08-26)

A rapid and sensitive method for measuring carboxypeptidase N (CPN) activity in human plasma is described. The procedure is based on the hydrolysis of a high-specificity/low-affinity substrate, hippuryl-L-lysine, to its products hippuric acid and lysine. The substrate and product are

Reaction of N(alpha)-hippuryllysine with 2-hydroxyheptanal: a model for lysine-directed protein modifications by lipid peroxidation.

Koichi Itakura et al.

Chemistry and physics of lipids, 124(2), 81-88 (2003-06-24)

2-Hydroxyheptanal (2-HH) is one of the major aldehydes derived from peroxidation of polyunsaturated fatty acids. In the present study, to obtain an insight into the contributions of 2-HH to protein modifications during lipid peroxidation, a lysine-containing dipeptide, N(alpha)-hippuryllysine (N-benzoylglycyl-L-lysine, BGL)

Human 'creatine kinase conversion factor' identified as a carboxypeptidase.

R J Edwards et al.

The Biochemical journal, 221(2), 465-470 (1984-07-15)

The effect of partially purified 'creatine kinase conversion factor' on rabbit muscle creatine kinase is shown to be that of a carboxypeptidase, removing the C-terminal lysine residue from both subunits. These changes fully explain the three-banded electrophoretic patterns of the

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Global Trade Item Number

SKU	GTIN
H6750-1G	04061833801765