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Merck
CN

H5882

Hexadecyltrimethylammonium bromide

≥98%

Synonym(s):

CTAB, Cetrimonium bromide, Cetyltrimethylammonium bromide, Palmityltrimethylammonium bromide

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About This Item

Linear Formula:
CH3(CH2)15N(Br)(CH3)3
CAS Number:
57-09-0
Molecular Weight:
364.45
UNSPSC Code:
12161900
NACRES:
NA.21
PubChem Substance ID:
24895714
EC Number:
200-311-3
Beilstein/REAXYS Number:
3598189
MDL number:
MFCD00011772

Key Documents

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Product Name

Hexadecyltrimethylammonium bromide, ≥98%

InChI key

LZZYPRNAOMGNLH-UHFFFAOYSA-M

InChI

1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1

SMILES string

[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C

description

cationic

assay

≥98%

form

(solids)

mol wt

micellar avg mol wt 62,000

aggregation number

170

technique(s)

DNA extraction: suitable
RNA extraction: suitable

pH

5.0-7 (25 °C, 36.4 g/L)

CMC

0.92 mM (20-25°C)

mp

248-251 °C (lit.)

solubility

H2O: 100 mg/mL

density

2.30 g/cm3

HLB

10

application(s)

genomic analysis

Quality Level

300

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Application

Hexadecyltrimethylammonium bromide has been used:
  • as a component in sodium phosphate buffer to homogenize tissues for determining myeloperoxidase activity
  • in the synthesis of gold nanorods with surface plasmon resonance for a comparative study
  • in the synthesis of gold nanorods to study the influence of good hexadecyltrimethylammonium bromide (CTAB) and CTAB with iodide impurities on the synthesis

Biochem/physiol Actions

Hexadecyltrimethylammonium bromide or cetyltrimethylammonium bromide (CTAB) can be used to isolate plant high molecular weight DNA (by a rapid method) as well as plant DNA for use in polymerase chain reaction (PCR) analysis. It plays a key role in precipitating nucleic acids. CTAB can be used as titrant for potentiometric titration of perchlorate. It can also be used as a phase-transfer catalyst in the reduction of arenes and heterocyclic compounds. It is suitable for determining protein molecular weights in electrophoretic systems. CTAB can also be used to determine critical micelle concentration of detergents.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Features and Benefits

  • Provides enhancement of concanavalin A mediated agglutination

General description

Hexadecyltrimethylammonium bromide, a bactericidal, is a cationic detergent. Its activity can be neutralized by soaps and anionic detergents. Cetyltrimethylammonium bromide (CTAB) is effective against Gram-positive and Gram-negative bacteria at alkaline pH.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3

target_organs

Gastrointestinal tract, Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

471.2 °F - closed cup

flash_point_c

244 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000523056
0000521695
0000521696
0000521695
0000521696

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Israa Haidar et al.
Physical chemistry chemical physics : PCCP, 18(47), 32272-32280 (2016-11-17)
The controlled assembly of anisotropic plasmonic nanoparticles (NPs) into highly SERS-active substrates remains particularly challenging for the production of long-term stable NP assemblies in suspension. In this work, we report a simple and efficient strategy to assemble gold nanorods (AuNRs)
K Maki et al.
Biochemical and biophysical research communications, 175(3), 768-774 (1991-03-29)
We investigated conditions for selective solubilization of the intermediate filament (IF) of BHK-21 cells, and found that a cationic detergent, cetyltrimethylammonium bromide (CTAB), was effective for rapid dissociation of IF into the monomeric form. More selective dissociation was performed with
Rodrigo Jiménez-Saiz et al.
Frontiers in immunology, 11, 155-155 (2020-03-03)
Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis. However, the impact of the microbiota on their frequency and function at mucosal sites remains unclear. Here, we investigated the role of the microbiota in the regulation of enteric
Raja Gopal Rayavarapu et al.
Langmuir : the ACS journal of surfaces and colloids, 26(7), 5050-5055 (2010-03-09)
Recent reports [Smith and Korgel Langmuir 2008, 24, 644-649 and Smith et al. Langmuir 2009, 25, 9518-9524] have implicated certain hexadecyltrimethylammonium bromide (CTAB) products with iodide impurities, in the failure of a seed-mediated, silver and surfactant-assisted growth protocol, to produce
J Werner et al.
Annals of surgery, 229(6), 834-840 (1999-06-11)
To analyze the time points and levels of the expression of adhesion molecules in the pancreas and lung in pancreatitis of different severities, and to assess whether treatment with a monoclonal antibody against intercellular adhesion molecule-1 (ICAM-1) can reduce local
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