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H5417

Sigma-Aldrich

Cytochrome P450 2C19, human

recombinant, expressed in E. coli

Synonym(s):

Cytochrome P450, purified, soluble, CYP2C19

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About This Item

CAS Number:
9035-51-2
UNSPSC Code:
12352204
NACRES:
NA.54

biological source

human

Quality Level

200

recombinant

expressed in E. coli

description

purified, soluble

form

liquid

specific activity

12-110 units/mg protein

mol wt

54783.3 g/mol

concentration

3.5-25 mg/mL protein
50-150 nmol/mL (P450)
6-14 nmol/mg protein (specific content)

NCBI accession no.

NP_00760.1

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CYP2C19(1557)

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General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Unit Definition

One unit will convert 1.0 nanomole of omeprazole (6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole) to 5-hydroxyomeprazole per minute at pH 7.4 at 37 °C.

Other Notes

Visit our drug metabolism resources: http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

WGK

WGK 2

Flash Point(F)

320.0 °F

Flash Point(C)

160 °C

Regulatory Information

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Certificates of Analysis (COA)

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