All Photos(1)
Synonym(s):
11β,17β-Dihydroxyandrost-4-en-3-one, 4-Androstene-11β,17β-diol-3-one
Empirical Formula (Hill Notation):
C19H28O3
CAS Number:
Molecular Weight:
304.42
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
form
crystalline
drug control
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
color
light yellow
SMILES string
CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2O
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Biochem/physiol Actions
Structure-activity relationships of 11-substituted testosterone derivatives as progesterone agonists, and their effect on growth and differentiation of human decidual cells.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
Certificates of Analysis (COA)
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D E Kime et al.
General and comparative endocrinology, 68(2), 189-196 (1987-11-01)
Testosterone, estradiol, and dehydroepiandrosterone (T, E2, and DHA) were measured by RIA in plasma samples from three groups of sexually immature male and female (male, female) river lampreys: (I) intact, (II) gonadectomized, or (III) with pro- and mesoadenohypophysis removed (hypophysectomized).
R K Brantley et al.
Hormones and behavior, 27(3), 332-347 (1993-09-01)
Plasma levels of 11-ketotestosterone, 11-beta-OH-testosterone, testosterone, and 17-beta-estradiol were measured in reproductive Porichthys notatus, a teleost fish with two male morphs and alternative reproductive tactics. The two male types had contrasting androgen profiles. 11-Ketotestosterone was the predominant androgen in the
S T Chan et al.
Journal of steroid biochemistry, 25(6), 1013-1021 (1986-12-01)
A new method for the simultaneous determination of androstenedione, testosterone, 11-oxotestosterone and 11 beta-hydroxy-testosterone in teleost plasma has been developed. Steroids extracted from the plasma were first separated by Celite chromatography using ethanediol as the stationary phase and different concentrations
R Schlaghecke et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 24(8), 577-581 (1986-08-01)
A radioimmunoassay (RIA) is described for the measurement of 11 beta,17 beta-dihydroxy-4-androsten-3-one (11 beta-hydroxytestosterone) in human plasma. The reliability criteria of the new RIA were similar to those of other steroid hormone radioimmunoassays. The mean plasma 11 beta,17 beta-dihydroxy-4-androsten-3-one level
T Leitz et al.
General and comparative endocrinology, 66(1), 145-157 (1987-04-01)
Testicular tissues of the Siamese fighting fish were incubated with [14C]pregnenolone for 10, 20, 30, 50, 80, and 120 min, and with [14C]progesterone, [14C]11 beta-hydroxyandrostenedione, [14C]11 beta-hydroxytestosterone, and [14C]androstenetrione for 120 min. 11-Ketotestosterone was the main metabolite in all 120-min
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