Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN
All Photos(1)

Key Documents

Safety Information

H3786

Sigma-Aldrich

3′-p-Hydroxypaclitaxel

95% (HPLC), solid

Sign Into View Organizational & Contract Pricing

Select a Size

150 MG
¥1,096.69

¥1,096.69


Please contact Customer Service for Availability


Select a Size

Change View
150 MG
¥1,096.69

About This Item

Empirical Formula (Hill Notation):
C47H51NO15
CAS Number:
Molecular Weight:
869.91
MDL number:
UNSPSC Code:
12161501

¥1,096.69


Please contact Customer Service for Availability

Quality Level

Assay

95% (HPLC)

form

solid

storage temp.

−20°C

InChI

1S/C47H51NO15/c1-24-31(61-43(57)36(53)35(27-17-19-30(51)20-18-27)48-41(55)28-13-9-7-10-14-28)22-47(58)40(62-42(56)29-15-11-8-12-16-29)38-45(6,32(52)21-33-46(38,23-59-33)63-26(3)50)39(54)37(60-25(2)49)34(24)44(47,4)5/h7-20,31-33,35-38,40,51-53,58H,21-23H2,1-6H3,(H,48,55)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1

InChI key

XKSMHFPSILYEIA-MZXODVADSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
T3320T6557T3559
clone

GTU-88, monoclonal

clone

polyclonal

clone

GTU-88, monoclonal

clone

polyclonal

species reactivity

rat, hamster, chicken, human, bovine, canine, Xenopus, mouse

species reactivity

human, frog, rat

species reactivity

rat, hamster, chicken, human, bovine, canine, Xenopus, mouse

species reactivity

human, chicken

biological source

mouse

biological source

rabbit

biological source

mouse

biological source

rabbit

antibody form

purified antibody (purified from hybridoma cell culture)

antibody form

IgG fraction of antiserum

antibody form

ascites fluid

antibody form

IgG fraction of antiserum

isotype

IgG1

isotype

-

isotype

IgG1

isotype

-

Application

Used for determining CYP3A4 activity.

Physical form

Each vial contains 20 nmoles (± 1%) (approx. 17.4 μg).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hiroaki Yamaguchi et al.
Biomedical chromatography : BMC, 27(4), 539-544 (2012-09-29)
A column-switching liquid chromatography/electrospray ionization tandem mass spectrometry to determine paclitaxel and its metabolites, 6α-hydroxypaclitaxel and p-3'-hydroxypaclitaxel, in human plasma was developed. The analytical system had a Shim-Pack MAYI-ODS (10 × 4.6 mm i.d.) trapping column with deproteinization ability that concentrates analytes and
Ryoko Taniguchi et al.
Journal of pharmacological sciences, 97(1), 83-90 (2005-01-19)
Paclitaxel is widely used for treatment of malignant tumors. Paclitaxel is metabolized by CYP2C8 and CYP3A4, and these enzymes are known to differ between individuals, although the details have not been clarified. Recent progress in pharmacogenetics has shown that genetic
Henrik Gréen et al.
Rapid communications in mass spectrometry : RCM, 20(14), 2183-2189 (2006-06-23)
A quantitative liquid chromatography/ion trap mass spectrometry method for the simultaneous determination of paclitaxel, 6alpha-hydroxypaclitaxel and p-3'-hydroxypaclitaxel in human plasma has been developed and validated. 6alpha-,p-3'-Dihydroxypaclitaxel was also quantified using paclitaxel as a reference and docetaxel as an internal standard.
M T Huizing et al.
Journal of chromatography. B, Biomedical applications, 674(2), 261-268 (1995-12-15)
A reversed-phase high-performance liquid chromatographic (HPLC) method has been validated for the quantitative determination of the three major paclitaxel metabolites (6 alpha-hydroxypaclitaxel, 3'-p-hydroxypaclitaxel, 6 alpha,3'-p-dihydroxypaclitaxel) in human plasma. The HPLC system consists of an APEX-octyl analytical column and acetonitrile-methanol-0.02 M
Heleen A Bardelmeijer et al.
Anti-cancer drugs, 14(3), 203-209 (2003-03-14)
Previous mass balance studies in humans and mice have shown that the fecal and urinary recovery of paclitaxel and known metabolites (3' -hydroxypaclitaxel, 6alpha-hydroxypaclitaxel and 3',6alpha-dihydroxypaclitaxel) was not complete. Obviously this discrepancy is caused by the existence of other yet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service