Skip to Content
Merck
CN
All Photos(1)

Key Documents

Safety Information

H141

Sigma-Aldrich

S(−)-8-Hydroxy-DPAT hydrobromide

solid

Synonym(s):

S(−)-8-OH-DPAT HBr

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H25NO · HBr
CAS Number:
Molecular Weight:
328.29
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

form

solid

optical activity

[α]25/D −67.8° in methanol(lit.)

color

white

SMILES string

Br.CCCN(CCC)[C@H]1CCc2cccc(O)c2C1

InChI

1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m0./s1

InChI key

BATPBOZTBNNDLN-UQKRIMTDSA-N

Biochem/physiol Actions

Partial 5-HT1A serotonin receptor agonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

L Björk et al.
Journal of medicinal chemistry, 32(4), 779-783 (1989-04-01)
The enantiomers of the N,N-dimethylamino (1), N,N-diethylamino (2), and N,N-dibutylamino (4) derivatives of 8-hydroxy-2-(dipropylamino)tetralin (8-OH DPAT; 3) have been synthesized. The compounds have been tested for activity at central 5-hydroxytryptamine and dopamine receptors by use of biochemical and behavioral tests
L J Cornfield et al.
Molecular pharmacology, 39(6), 780-787 (1991-06-01)
Although many different types of compounds have been tested for 5-hydroxytryptamine1A (5-HT1A) binding affinity, much remains to be learned about the structural requirements associated with 5-HT1A agonism, partial agonism, and antagonism. The present study uses the forskolin-stimulated adenylate cyclase (FSC)
Huiyi H Chang et al.
Experimental neurology, 239, 210-217 (2012-10-27)
Trauma to the thoracolumbar spine commonly results in injuries to the cauda equina and the lumbosacral portion of the spinal cord. Both complete and partial injury syndromes may follow. Here, we tested the hypothesis that serotonergic modulation may improve voiding
M Jerry Wright et al.
PloS one, 7(8), e44652-e44652 (2012-09-07)
The drug 4-methylmethcathinone (4-MMC; aka, mephedrone, MMCAT, "plant food", "bath salts") is a recent addition to the list of popular recreational psychomotor-stimulant compounds. Relatively little information about this drug is available in the scientific literature, but popular media reports have
Otto Kalliokoski et al.
PloS one, 8(3), e58460-e58460 (2013-03-19)
The metabolism cage is a barren, non-enriched, environment, combining a number of recognized environmental stressors. We investigated the ability of male BALB/c mice to acclimatize to this form of housing. For three weeks markers of acute and oxidative stress, as

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service